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XB-ANTIBODY-29208978

Antibody Name: h3-3a Ab43

Common Name: H3K27me3

RRID: AB_2943245
Synonyms: Tri-Methyl-Histone H3 (Lys27)

Antigens
Gene: h3-3a

Clone Type: Monoclonal
Source: Cell Signaling Technology

Antibody
Clone Number C36B11
Purification
Isotype IgG
Host Organism rabbit
Xenopus Reactivity X. laevis
Non-Xenopus Reactivity human, monkey, mouse, rat
Description: Tri-Methyl-Histone H3 (Lys27) (C36B11) Rabbit mAb detects endogenous levels of histone H3 only when tri-methylated on Lys27. The antibody does not cross-react with non-methylated, mono-methylated or di-methylated Lys27. In addition, the antibody does not cross-react with mono-methylated, di-methylated or tri-methylated histone H3 at Lys4, Lys9, Lys36 or Histone H4 at Lys20.
Immunogen
Name h3-3a K27me3
Type synthetic sequence
Post Translational Modifications Methylated
Source Organism Other
Description Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to the amino terminus of histone H3 in which Lys27 is tri-methylated.
Sequence
Reported Usage
chromatin immunoprecipitation
Publications
First: BAP1 regulates epigenetic switch from pluripotency to differentiation in developmental lineages giving rise to BAP1-mutant cancers., Sci Adv 2019          
Most recent:
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