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Summary Attributions Wiki
XB-MORPHOLINO-22064432
Morpholino Name: kmt2d MO1
Synonyms:
Target mRNA: kmt2d

Morpholino Type: translation blocking morpholino
Sequence: 5' GCCTTTTGTTCATCCATTCCTGTTC 3'

Source: Gene Tools LLC


Target mRNA tropicalis laevis.L laevis.S
Identities 23/25 25/25 23/25
genome
MO
 
5' GAAAAGGAATGGATGAACAAAAAGC 3'
   ||| |||||||||||||||||| ||
3' CTTGTCCTTACCTACTTGTTTTCCG 5'
 
5' GAACAGGAATGGATGAACAAAAGGC 3'
   |||||||||||||||||||||||||
3' CTTGTCCTTACCTACTTGTTTTCCG 5'
 
5' AAACAGGAATGGATGAACAAAAAGC 3'
    ||||||||||||||||||||| ||
3' CTTGTCCTTACCTACTTGTTTTCCG 5'
    
Genomic Alignments Position Identity Strand Target Target mRNA
laevis 10.1 Chr2L:143038649..143038673 25/25 Sense target kmt2d.L
Chr2S:127985623..127985647 23/25 Sense target kmt2d.S
Chr1L:141564158..141564182 21/25 Sense off-target anxa1.1.L
Chr2S:71542341..71542365 22/25 Antisense unknown
Chr7L:90469361..90469385 22/25 Antisense unknown
tropicalis 10.0 Chr2:136415065..136415089 23/25 Sense target kmt2d
Chr5:151723791..151723815 23/25 Sense off-target kif13b
Chr3:47991450..47991474 22/25 Antisense off-target cdc25c
Chr9:65148131..65148155 21/25 Antisense unknown
Chr5:4434807..4434831 21/25 Sense unknown
Publications
???morpholino.displaySummary.papersFirst??? Loss of function of Kmt2d, a gene mutated in Kabuki syndrome, affects heart development in Xenopus laevis., Dev Dyn 2019     
???morpholino.displaySummary.papersRecent??? The histone methyltransferase KMT2D, mutated in Kabuki syndrome patients, is required for neural crest cell formation and migration., Hum Mol Genet 2020     
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