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Summary Attributions Wiki
XB-GRNA-25900334
gRNA Name: itsn1 gRNA3
Synonyms:
Genomic Target: itsn1

Sequence: 5' CATCTGGGCCATAACAGTGG 3'



Genomic Target tropicalis laevis.L laevis.S
Identities 20/20 19/20 19/20
genome
gRNA
 
5' CCACTGTTATGGCCCAGATG 3'
   ||||||||||||||||||||
3' GGTGACAATACCGGGTCTAC 5'
 
5' CCACCGTTATGGCCCAGATG 3'
   |||| |||||||||||||||
3' GGTGACAATACCGGGTCTAC 5'
 
5' CCACCGTTATGGCCCAGATG 3'
   |||| |||||||||||||||
3' GGTGACAATACCGGGTCTAC 5'
    
Genomic Alignments Position Identity Strand Target Genomic Target
laevis 10.1 Chr2L:13780303..13780322 19/20 Antisense target itsn1.L
Chr2S:20201468..20201487 19/20 Sense target itsn1.S
Chr2L:150641666..150641685 17/20 Antisense unknown
tropicalis 10.0 Chr2:14164959..14164978 20/20 Sense target itsn1
Chr10:12017505..12017524 16/20 Antisense off-target hoxb2
Publications
???morpholino.displaySummary.papersFirst??? Identification and validation of candidate risk genes in endocytic vesicular trafficking associated with esophageal atresia and tracheoesophageal fistulas., HGG Adv 2022     
???morpholino.displaySummary.papersRecent??? Disrupted endosomal trafficking of the Vangl-Celsr polarity complex underlies congenital anomalies in Xenopus trachea-esophageal morphogenesis., Dev Cell 2025     
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