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Figure 9. I203T mutant stability cannot be rescued by the WT.(A) Homomeric I203T hexamers and dodecamers are unstable. Both EM and Blue Native western analyses clearly showed no rescuing the I203T mutant hemichannels, even at the very high ratio of 2 (B), where the majority of the heteromer subunits should contain WT.

Image published in: Ambrosi C et al. (2013)

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