Fig. 3 B

Willsey HR et al. (2020)

Xtr WT + dyrk1a CRISPR

NF46 (RNA-Seq)

Expression Phenotype

increased amount dlc expression in brain
decreased amount fos expression in brain
decreased amount hoxc6 expression in brain
decreased amount myl1 expression in brain
decreased amount mylpf expression in brain
decreased amount npas4 expression in brain
decreased amount ocm4.4 expression in brain
decreased amount scn2b expression in brain
decreased amount tnni2 expression in brain
decreased amount tnnt3 expression in brain
increased amount apoe expression in brain
increased amount aurkb expression in brain
increased amount ccnb1.2 expression in brain
increased amount ccnb2 expression in brain
increased amount cdca7 expression in brain
increased amount cdk1 expression in brain
increased amount cfd expression in brain
increased amount cks1b expression in brain
increased amount colec12 expression in brain
increased amount ly6g6c expression in brain
increased amount pimreg expression in brain
increased amount rbp4 expression in brain

fig.7.i, j

Maguire RJ et al. (2012)

Xla Wt + myod1 MO

NF13 (in situ hybridization)

Expression Phenotype
decreased amount dlc.L expression in paraxial mesoderm

fig.7.l, m

Maguire RJ et al. (2012)

Xla Wt + myod1 MO

NF19 (in situ hybridization)

Anatomical Phenotype
abnormally anteriorly mislocalised somite

Expression Phenotype
mislocalised dlc.L expression in somite