Fig. 1C c4

Hyatt BA et al. (2025)

Xla Wt + Tg(Hsa.NKX2-1-GR) [FG]

NF39 (in situ hybridization)

Expression Phenotype
absent fabp2.L expression in midgut primordium increased amount sftpc.L expression in lung bud mislocalised sftpc.L expression in foregut endoderm mislocalised sftpc.L expression in hindgut endoderm mislocalised sox2.L expression in hindgut endoderm mislocalised sox2.L expression in midgut

Fig.1C c2

Hyatt BA et al. (2025)

Xla Wt + Tg(Xla.nkx2-1-GR) [FG]

NF39 (in situ hybridization)

Expression Phenotype
decreased amount fabp2.L expression in midgut primordium decreased amount cdx2.L expression in midgut primordium mislocalised sftpc.L expression in foregut endoderm mislocalised sftpc.L expression in hindgut endoderm mislocalised sox2.L expression in midgut

Figh. 1C c3

Hyatt BA et al. (2025)

Xla Wt + Tg(Xla.nkx2-1-GR) [HG]

NF39 (in situ hybridization)

Expression Phenotype
decreased amount fabp2.L expression in midgut primordium decreased amount cdx2.L expression in midgut primordium mislocalised sftpc.L expression in hindgut mislocalised sox2.L expression in dorsal lateral plate mesoderm

Fig. 2 B

Ismail T et al. (2024)

Xla Wt +PFOS

NF35/36-37/38 (RNA-Seq)

Expression Phenotype

decreased amount fabp2.L expression in the embryo
decreased amount c5ar1.L expression in embryo
decreased amount ddit4l.S expression in embryo
decreased amount foxd3.L expression in the embryo
decreased amount rnf112.L expression in embryo
decreased amount slc14a2.L expression in embryo
increased amount amy2a.L expression in the embryo
increased amount ass1.L expression in the embryo
increased amount cxcl8a.1.L expression in the embryo
increased amount olfm4.L expression in the embryo
increased amount uts2.L expression in the embryo
increased amount arg1.L expression in embryo
increased amount otc.L expression in embryo
increased amount pla2g1b.L expression in embryo