Fig. 3 AB

Fogliano C et al. (2026)

XLA WT + GD

NF45-46 (RT-PCR)

Expression Phenotype

increased amount il1b.L expression in whole organism
decreased amount fgf8.L expression in whole organism
decreased amount pax6.L expression in whole organism
decreased amount sox9.L expression in whole organism
increased amount abcb1.L expression in whole organism
increased amount bmp4.L expression in whole organism
increased amount egr2.L expression in whole organism
increased amount rax.L expression in whole organism
increased amount rela.L expression in whole organism
increased amount tnf.L expression in whole organism

Fig. 3 CD

Fogliano C et al. (2026)

XLA WT + GD

NF45-46 (RT-PCR)

Expression Phenotype
increased amount il1b.L expression in whole organism increased amount abcb1.L expression in whole organism increased amount egr2.L expression in whole organism increased amount rax.L expression in whole organism increased amount rela.L expression in whole organism

Fig. 4. BEH

Garvey Griffith CN et al. (2025)

Xla wt juvenile + skin wound + rCSF1

juvenile [7dpw] (in situ hybridization)

Anatomical Phenotype
increased cell population proliferation in lymphocyte increased cell population proliferation in migrating macrophage increased cell population proliferation in neutrophil

Expression Phenotype

increased amount il1b.L expression in wound epidermis
increased amount il1b.S expression in wound epidermis
decreased amount ccl4.L expression in wound epidermis
decreased amount cxcr4.L expression in wound epidermis
decreased amount il23r.L expression in wound epidermis
decreased amount tnf.L expression in wound epidermis
increased amount csf3r.L expression in wound epidermis
increased amount cxcl8a.2.L expression in wound epidermis
increased amount cxcl8a.L expression in wound epidermis
increased amount cxcl8a.S expression in wound epidermis
increased amount il17re.L expression in wound epidermis
increased amount il17re.S expression in wound epidermis
increased amount mpo.L expression in wound epidermis