nkx2-5 has 25 expression phenotype(s)
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Images Sources Experiment + Assay Phenotypes Human Diseases
Fig. S4 Ar2c3

Griffin C et al. (2025) 		Xtr Wt + sf3b4 CRISPR

NF29/30 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5 expression in lateral plate mesoderm
Fig. S4A r3c3

Griffin C et al. (2025) 		Xtr Wt + sf3b4 CRISPR

NF35/36 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5 expression in heart primordium
Fig. 3 F c3

Berger H et al. (2024) 		Xla Wt + fbrsl1 MO (sb)

NF24 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5.L expression in heart primordium
Fig. 2 A

Ismail T et al. (2024) 		Xla Wt +PFOS

NF35/36 (in situ hybridization)
Expression Phenotype
increased amount nkx2-5.L expression in heart
increased amount ldlrap1.L expression in liver primordium
increased amount pax6.L expression in eye
increased amount pax6.L expression in forebrain
increased amount pax6.L expression in hindbrain
increased amount pax6.L expression in midbrain-hindbrain boundary
increased amount pax6.L expression in olfactory region
increased amount sox3.L expression in forebrain
increased amount sox3.L expression in midbrain-hindbrain boundary
No Image Fig. 8A

Flach H et al. (2022) 		Xla Wt + glyphosate [121.5]

NF20 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5.L expression in cardiac progenitor cell
decreased amount isl1.L expression in cardiac progenitor cell
No Image Fig.8BC

Flach H et al. (2022) 		Xla Wt + glyphosate [121.5]

NF28 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5.L expression in heart primordium
decreased amount acta1.L expression in heart primordium
decreased amount isl1.L expression in heart primordium
decreased amount myh6.L expression in heart primordium
No Image Fig. 8A

Flach H et al. (2022) 		Xla Wt + glyphosate [243]

NF20 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5.L expression in cardiac progenitor cell
decreased amount isl1.L expression in cardiac progenitor cell
No Image Fig. 8BC

Flach H et al. (2022) 		Xla Wt + glyphosate [243]

NF28 (in situ hybridization)
Expression Phenotype
decreased amount nkx2-5.L expression in heart primordium
decreased amount acta1.L expression in heart primordium
decreased amount isl1.L expression in heart primordium
decreased amount myh6.L expression in heart primordium
Fig.S3.B,C

Wang H et al. (2021) 		Xla Wt + fermt2 MO

NF32 (in situ hybridization)
Anatomical Phenotype
abnormal development of heart
Expression Phenotype
decreased amount nkx2-5.L expression in heart
Fig. 7 D G

Schwenty-Lara J et al. (2019) 		Xla Wt + kmt2d MO

NF28 (in situ hybridization)
Anatomical Phenotype
abnormal development of heart primordium
Expression Phenotype
decreased amount nkx2-5.L expression in heart primordium
congenital heart disease
Kabuki syndrome