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XB-PHENO-25210

Xtr Wt + CYCLOPAMINE, Willsey HR et al. (2021)

Experiment + Assay: Xtr Wt + CYCLOPAMINE + brain NF46 (RNA-Seq (RNA))
Background: Xtr.NigerianNasco
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
chemical Cyclopamine
NF stage 29 and 30 embryo
Conditions:
Assay Type Assay Stages Antibody
RNA-Seq NF stage 46  
Expression Phenotypes (363):
increased amount a2m expression in the brain
increased amount abo.1 expression in the brain
increased amount acod1la expression in the brain
increased amount acod1lb expression in the brain
increased amount acp4 expression in the brain
increased amount acp7 expression in the brain
increased amount acta4 expression in the brain
increased amount actc1 expression in the brain
increased amount acy3 expression in the brain
increased amount adap1l expression in the brain
increased amount ag1 expression in the brain
increased amount agr2 expression in the brain
increased amount agr3 expression in the brain
increased amount agtrap expression in the brain
increased amount ahnak2 expression in the brain
increased amount amdhd2 expression in the brain
increased amount anxa1.2 expression in the brain
increased amount anxa9 expression in the brain
increased amount aoah expression in the brain
increased amount apoe expression in brain
increased amount aqp3 expression in the brain
increased amount arhgap30 expression in the brain
decreased amount arr3 expression in the brain
increased amount arsa.1 expression in the brain
decreased amount asmt expression in the brain
increased amount atp12a expression in the brain
increased amount atp12a-like expression in the brain
increased amount atp2a1 expression in the brain
increased amount atp8b1 expression in the brain
increased amount bcl10 expression in the brain
increased amount bcl2l14 expression in the brain
increased amount bglap2 expression in the brain
increased amount c10orf53 expression in the brain
increased amount c19orf33 expression in the brain
increased amount c1r expression in the brain
increased amount c3 expression in the brain
increased amount c6.2 expression in the brain
increased amount c7 expression in the brain
increased amount c8g expression in the brain
increased amount capn13 expression in the brain
increased amount capn8.3 expression in the brain
increased amount casq1 expression in the brain
increased amount cblc expression in the brain
increased amount ccl4 expression in the brain
increased amount ccl5 expression in the brain
decreased amount ccndx expression in the brain
increased amount cd164l2 expression in the brain
increased amount cd28 expression in the brain
increased amount cdh1 expression in the brain
increased amount cdh3 expression in the brain
increased amount cfb expression in the brain
decreased amount cga expression in the brain
increased amount ch25h expression in the brain
increased amount chit1 expression in the brain
increased amount cideb expression in the brain
increased amount ckm expression in the brain
increased amount clca3p expression in the brain
increased amount cldn3 expression in the brain
increased amount cldn4 expression in the brain
increased amount cldn6.1 expression in the brain
increased amount cldn8.2 expression in the brain
increased amount cldn8.3 expression in the brain
increased amount clec3b expression in the brain
increased amount clu expression in the brain
increased amount cnfn.1 expression in the brain
increased amount cnksr1 expression in the brain
increased amount col17a1 expression in the brain
increased amount col1a1 expression in the brain
increased amount col1a2 expression in the brain
increased amount col3a1 expression in the brain
increased amount col6a2 expression in the brain
increased amount cpn1 expression in the brain
increased amount crisp1.4 expression in the brain
increased amount crybg1 expression in the brain
increased amount csf1 expression in the brain
increased amount ctgfl expression in the brain
increased amount ctsc expression in the brain
increased amount ctsk expression in the brain
increased amount ctsz expression in the brain
increased amount cxc8b.1 expression in the brain
increased amount cxcl8a.1 expression in the brain
increased amount cyp27a1 expression in the brain
increased amount cyp3a4.1 expression in the brain
increased amount cyp3a4.2 expression in the brain
increased amount cyp4b1.5 expression in the brain
increased amount dan4l expression in the brain
decreased amount dbx1 expression in the brain
decreased amount dbx2 expression in the brain
increased amount dcn expression in the brain
increased amount dok2 expression in the brain
increased amount duox1 expression in the brain
increased amount ebi3 expression in the brain
increased amount elf3 expression in the brain
increased amount elovl7 expression in the brain
increased amount epcam expression in the brain
increased amount epgn expression in the brain
increased amount epsti1 expression in the brain
increased amount esrp1 expression in the brain
increased amount evpl expression in the brain
increased amount f2rl1 expression in the brain
increased amount fam3d expression in the brain
increased amount fam83c expression in the brain
increased amount fam83f expression in the brain
increased amount fermt1 expression in the brain
increased amount fgfbp1 expression in the brain
increased amount fgfbp2 expression in the brain
increased amount fmnl1 expression in the brain
increased amount fndc7 expression in the brain
decreased amount fosb expression in the brain
decreased amount foxd2 expression in the brain
increased amount gatd3ala expression in the brain
increased amount gatd3alb.1 expression in the brain
decreased amount gh1 expression in the brain
decreased amount gh2 expression in the brain
increased amount gjb2 expression in the brain
decreased amount gli1 expression in the brain
decreased amount gnat1 expression in the brain
increased amount gnpda1 expression in the brain
increased amount gpa33 expression in the brain
increased amount gpnmb expression in the brain
increased amount gpr160 expression in the brain
increased amount gpr20 expression in the brain
increased amount gpr84 expression in the brain
increased amount gpx2 expression in the brain
increased amount grhl1 expression in the brain
increased amount grhl3 expression in the brain
increased amount havcr1 expression in the brain
decreased amount helt expression in the brain
decreased amount hes7.1 expression in the brain
decreased amount hhip expression in the brain
increased amount hmx1 expression in the brain
increased amount hoxb6 expression in the brain
increased amount hoxb7 expression in the brain
increased amount hoxb9 expression in the brain
increased amount hoxc6 expression in the brain
increased amount hps4 expression in the brain
increased amount hpse expression in the brain
increased amount hsd17b14 expression in the brain
increased amount htra3 expression in the brain
increased amount htra4 expression in the brain
increased amount ier3 expression in the brain
increased amount ifi30 expression in the brain
increased amount il11 expression in the brain
increased amount il1b expression in the brain
increased amount il1r1 expression in the brain
increased amount il4r expression in the brain
increased amount kcne3 expression in the brain
increased amount kremen2 expression in the brain
increased amount krt12.2 expression in the brain
increased amount krt12.3 expression in the brain
increased amount krt12.5 expression in the brain
increased amount krt15.2 expression in the brain
increased amount krt17 expression in the brain
decreased amount krt61 expression in the brain
increased amount krt62 expression in the brain
increased amount lacc1 expression in the brain
increased amount lamb4 expression in the brain
increased amount lamp3 expression in the brain
increased amount lgals1.1 expression in the brain
increased amount lgals12 expression in the brain
increased amount lgals3 expression in the brain
increased amount lgals9c expression in the brain
decreased amount lhx6 expression in the brain
decreased amount lhx8 expression in the brain
increased amount litafd expression in the brain
increased amount lmcd1 expression in the brain
increased amount lox expression in the brain
increased amount lrmda expression in the brain
increased amount lrrn4cl expression in the brain
increased amount ltbr expression in the brain
increased amount lum expression in the brain
increased amount ly6g6c expression in brain
increased amount mal2 expression in the brain
increased amount mal expression in the brain
increased amount mall expression in the brain
increased amount mapk13 expression in the brain
increased amount me1 expression in the brain
increased amount mgat4g expression in the brain
increased amount mgc147117 expression in the brain
increased amount mgc75872 expression in the brain
increased amount mlana expression in the brain
increased amount mlkl expression in the brain
increased amount mlph expression in the brain
increased amount mmp13l expression in the brain
increased amount mmp1 expression in the brain
increased amount mpo expression in the brain
increased amount msln expression in the brain
increased amount msmb.1 expression in the brain
increased amount mst1r expression in the brain
increased amount muc22 expression in the brain
increased amount muc4 expression in the brain
increased amount myd88 expression in the brain
increased amount myh1 expression in the brain
increased amount myl1 expression in the brain
increased amount mylpf expression in the brain
increased amount myof.1 expression in the brain
increased amount napsa expression in the brain
increased amount neurl3 expression in the brain
decreased amount neurog3 expression in the brain
increased amount nfkbiz expression in the brain
increased amount nipal3 expression in the brain
decreased amount nkx2-8 expression in the brain
increased amount nmi expression in the brain
increased amount noxa1 expression in the brain
increased amount noxo1.2 expression in the brain
increased amount noxo1 expression in the brain
increased amount nrros expression in the brain
decreased amount ntn3 expression in the brain
decreased amount nxnl1 expression in the brain
increased amount oc90 expression in the brain
increased amount ocm1 expression in the brain
increased amount ocm4.1 expression in the brain
increased amount ocm4.2 expression in the brain
increased amount ocm4.3 expression in the brain
increased amount ocm4.4 expression in the brain
increased amount ocm4.5 expression in the brain
increased amount ocm4.6 expression in the brain
increased amount olfm4 expression in the brain
decreased amount opn4 expression in the brain
decreased amount opnpl [provisonal] expression in the brain
increased amount otogl2 expression in the brain
increased amount ouro1 expression in the brain
increased amount ouro2 expression in the brain
increased amount p2rx4 expression in the brain
increased amount pck1 expression in the brain
increased amount pecam1 expression in the brain
increased amount pglyrp1 expression in the brain
increased amount phyhdla.1 expression in the brain
increased amount phyhdla.2 expression in the brain
increased amount phyhdla.3 expression in the brain
increased amount phyhdlb expression in the brain
increased amount pik3r5 expression in the brain
increased amount plek expression in the brain
increased amount plekho2 expression in the brain
increased amount pmel expression in the brain
increased amount postn expression in the brain
decreased amount pou1f1 expression in the brain
increased amount pparg expression in the brain
increased amount pram1 expression in the brain
decreased amount prl.1 expression in the brain
decreased amount prl.2 expression in the brain
increased amount prss1.2 expression in the brain
increased amount prss16 expression in the brain
increased amount prss27 expression in the brain
increased amount prss8l.5 loc108703873 expression in the brain
increased amount prtn3-like.2 expression in the brain
increased amount psme1 expression in the brain
increased amount psme2 expression in the brain
decreased amount ptch2 expression in the brain
increased amount ptk6 expression in the brain
increased amount ptprh expression in the brain
increased amount pycard expression in the brain
increased amount rab38 expression in the brain
decreased amount rag1 expression in the brain
increased amount rassf6 expression in the brain
decreased amount rcvrn.2 expression in the brain
increased amount rgs10 expression in the brain
increased amount rgs1 expression in the brain
increased amount rhcg expression in the brain
increased amount ripk3l.1 expression in the brain
increased amount rnf128 expression in the brain
increased amount s100a1 expression in the brain
increased amount satpa expression in the brain
increased amount scnn1a expression in the brain
increased amount selp expression in the brain
decreased amount sfrp1 expression in the brain
increased amount sh2d4b expression in the brain
increased amount sh3bgr expression in the brain
increased amount siglec1 expression in the brain
increased amount slc11a1 expression in the brain
increased amount slc18a1 expression in the brain
increased amount slc22a8 expression in the brain
increased amount slc2a3 expression in the brain
increased amount slc2a6 expression in the brain
increased amount slc35d2 expression in the brain
increased amount slc44a4 expression in the brain
increased amount slc8b1 expression in the brain
increased amount smim22 expression in the brain
increased amount socs3 expression in the brain
increased amount soho1 expression in the brain
increased amount spink2 expression in the brain
increased amount spint1 expression in the brain
increased amount spint2 expression in the brain
decreased amount spon2 expression in the brain
increased amount st14 expression in the brain
increased amount st6gal1 expression in the brain
increased amount stab1 expression in the brain
increased amount stab2 expression in the brain
increased amount stoml3 expression in the brain
increased amount styk1 expression in the brain
increased amount sytl1 expression in the brain
increased amount tcap expression in the brain
increased amount thdl17 expression in the brain
increased amount thdl18 expression in the brain
increased amount tlrs5 expression in the brain
increased amount tmem30b expression in the brain
increased amount tmem44 expression in the brain
increased amount tmprss2.13 expression in the brain
increased amount tmprss2.14 expression in the brain
increased amount tmprss2.2 expression in the brain
increased amount tmprss2.5 expression in the brain
increased amount tmprss9 expression in the brain
increased amount tnfrsf10b expression in the brain
increased amount tnnc2 expression in the brain
increased amount tnni2 expression in the brain
increased amount tnnt3 expression in the brain
increased amount tom1l1 expression in the brain
increased amount tp63 expression in the brain
increased amount tprg1 expression in the brain
increased amount traf1 expression in the brain
increased amount trappc3l expression in the brain
increased amount trdn expression in the brain
increased amount trim29 expression in the brain
decreased amount tshb expression in the brain
increased amount tspan1 expression in the brain
increased amount tspan36 expression in the brain
increased amount ttr expression in the brain
increased amount txn expression in the brain
increased amount tyr expression in the brain
increased amount tyrp1 expression in the brain
increased amount ucp2 expression in the brain
increased amount upk1b expression in the brain
increased amount upk2 expression in the brain
increased amount upk3a expression in the brain
increased amount uts2b expression in the brain
increased amount uts2 expression in the brain
decreased amount vax1 expression in the brain
decreased amount vax2 expression in the brain
increased amount vgll1 expression in the brain
decreased amount vil1 expression in the brain
decreased amount vsx1 expression in the brain
increased amount vtcn1 expression in the brain
increased amount wfdc2 expression in the brain
increased amount xa-1 expression in the brain
increased amount XB1000829 [provisional] expression in the brain
increased amount XB22063314 [provisional:yrdc] expression in the brain
increased amount XB22068624 [provisional] expression in the brain
increased amount XB22169600 [provisional] expression in the brain
increased amount XB5717875 [provisional:plac8] expression in the brain
increased amount XB5719931 [provisional] expression in the brain
increased amount XB5729910 [provisional] expression in the brain
increased amount XB5734924 [provisional] expression in the brain
increased amount XB5740125 [provisional:tspan3] expression in the brain
increased amount XB5756214 [provisional:mr1] expression in the brain
increased amount XB5789557 [provisional] expression in the brain
increased amount XB5793597 [provisional] expression in the brain
increased amount XB5809687 [provisional] expression in the brain
increased amount XB5892933 [provisional:prss27.3] expression in the brain
increased amount XB5897453 [provisional:fcgbp] expression in the brain
increased amount XB5932119 [provisional] expression in the brain
increased amount XB5947741 [provisional] expression in the brain
increased amount XB5953580 [provisional] expression in the brain
increased amount XB5965586 [provisional:nfkbiz] expression in the brain
increased amount XB5967085 [provisional] expression in the brain
increased amount XB5993342 [provisional:ist1] expression in the brain
increased amount XB5993457 [provisional:aqp4] expression in the brain
increased amount XB956263 [provisional:mapk12] expression in the brain
increased amount XB987888 [provisional:muc5ac] expression in the brain
increased amount XB990108 [provisional] expression in the brain
increased amount XB990656 [provisional:adam9] expression in the brain
increased amount zc3h12a expression in the brain
decreased amount zgrf1 expression in the brain
increased amount znf534 expression in the brain
GEO Series: GSE155553: Xenbase, NCBI
Article: XB-ART-57754, PubMed