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XB-PHENO-25366

Xla Wt + gdf6 MO, Hanel ML and Hensey C (2006)

Experiment + Assay: Xla Wt + gdf6 MO + NF41 (immunohistochemistry)
Background: Xla.Outbred
Manipulations:
Manipulation Type Reagent Target Gene Stage Treatment Area
morpholino injection gdf6 MO1 gdf6 (Xla)
 NF stage 2- blastomere
Conditions:
Assay Type Assay Stages Antibody
immunohistochemistry NF stage 41  
Anatomical Phenotypes: abnormal eye morphology, abnormal retinal layer, absent amacrine cell, absent retinal ganglion cell, decreased cell population proliferation in eye, decreased size of the eye
Expression Phenotypes (2):
decreased amount hspa5.L expression in photoreceptor layer
decreased amount ncam1.L expression in cytoplasm
Source: Fig.2.B,D,F,H
Article: XB-ART-34383, PubMed