Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.icam5em2Horb | X. tropicalis | icam5 | 2nd Xtropicalis line with CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line tr... | NXR |
| Xtr.hs6st1emNXR | X. tropicalis | hs6st1 | CRISPR knockout of hs6st1 (heparan sulfate 6-O-sulfotransferase 1) gene. Mutation not yet characteri... | NXR |
| Xtr.gdf1em3Horb | X. tropicalis | gdf1 | CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom m... | NXR |
| Xla.dmrt1em4NXR | X. laevis | dmrt1.L dmrt1.S | Double X. levis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... | NXR |
| Xla.ccdc69wem3NXR | X. laevis | 3rdof 3 CRISPR line targeting the male sex determination gene ccdc69w developed by the NXR. Germ lin... | NXR | |
| Xla.ccdc69wem2NXR | X. tropicalis | 2nd of 3 CRISPR line targeting the male sex determination gene ccdc69w developed by the NXR. Germ li... | NXR | |
| Xla.ccdc69wem1NXR | X. laevis | CRISPR line targeting the male sex determination gene ccdc69w. Germ line transmission confirmed . A... | NXR | |
| Xtr.cbsemNXR | X. tropicalis | cbs | Custom CRISPR generated by NXR, targeting the cbs (cystathionine-beta-synthase) gene, | NXR |
| Xbo.dmrt1em2NXR | X. borealis | 2ndor 2 X. borealis CRISPR line bred by NXR, targeting dmrt1 (doublesex and mab-3 related transcript... | NXR | |
| Xbo.dmrt1em1NXR | X. borealis | 1 or 2 X. borealis CRISPR line bred by NXR, targeting dmrt1 (doublesex and mab-3 related transcripti... | NXR | |
| Xtr.snai2em3NXR | X. tropicalis | snai2 | 3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... | NXR |
| Xtr.snai2 em2NXR | X. tropicalis | snai2 | CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... | NXR |
| Xtr.sobp[em2NXR] | X. tropicalis | sobp | 2nd of 2 CRISPR knockout of sobp (sine oculis binding protein homolog ) X. tropicalis lines held by ... | NXR |
| Xtr.syngap1 emNXR | X. tropicalis | syngap1 | CRISPR line targeting syngap1 (). Not screened for mutation or germ line transmission yet. Contact t... | NXR |
| Xla.tcf3emNXR | X. laevis | tcf3.L | X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f... | NXR |
| Xla.tbx21emNXR | X. laevis | tbx21.L tbx21.S | double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. germ line transmission snd mutatio... | NXR |
| Xla.tap2emNXR | X. laevis | tap2.L tap2.S | X. laevis CRISPR line targeting tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.tap1emNXR | X. laevis | tap1.L | X. laevis CRISPR line targeting tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), a... | NXR |
| Xla.tracemHorb | X. laevis | trac.S | X. laevis CRISPR line targeting trac.S (T cell receptor alpha constant), a gene associated with immu... | NXR |
| Xla.velo1emNXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized . Germ lin... | NXR |
| Xla.wnt3em2NXR | X. laevis | wnt3.L | X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm... | |
| Xla.wnt3em1NXR | X. laevis | wnt3.S | X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... | NXR |
| Xtr.wnt3em1NXR | X. tropicalis | wnt3 | CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed, mutation... | NXR |
| Xtr.xbp1em2NXR | X. tropicalis | xbp1 | 2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1, a gene assocaited with Major Affec... | NXR |
| Xtr.sox2em2Horb | X. tropicalis | CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... | NXR | |
| Xtr.shroom3em2Horb | X. tropicalis | shroom3 | CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... | NXR |
| Xla.scanwemNXR | X. laevis | CRISPR knock out of the male sex determining gene, scan-w. Animals carry a 20bp deletion in scanw. ... | NXR | |
| Xtr.ripply3em2NXR | X. tropicalis | ripply3 | 2nd of 2 ripply3 lines at the NXR, CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ l... | NXR |
| Xtr.prph2em2Horb | X. tropicalis | prph2 | 2nd X. tropicalis line with CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Co... | NXR |
| Xtr.pou4f1em2NXR | X. tropicalis | pou4f1 | Custom CRISPR Xtropicalis line carrying a single 1bp insertion in pou4f1 (POU class 4 homeobox 1) ge... | NXR |
| Xla.pkhd1em3Horb | X. laevis | pkhd1.L | 3rd of 3 X. laevis CRISPR lines for pkhd1 (ciliary IPT domain containing fibrocystin/polyductin) gen... | NXR |
| Xla.pkhd1em2Horb | X. laevis | pkhd1.L | CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... | NXR |
| Xla.pax7em3Horb | X. laevis | pax7.L pax7.S | 3rd Xlaevis pax7 mutant line at the NXR. CRISPR knockout of pax7 (paired box 7). Germ line transmiss... | NXR |
| Xla.pax7em2Horb | X. laevis | pax7.L pax7.S | CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a -22bp dele... | NXR |
| Xtr.notch4 em2Horb | X. tropicalis | notch4 | the 2nd of 2 notch4 lines in X. tropicalis being bred by Horb lab. Contact NXR for details. | NXR |
| Xtr.nagluem3NXR) | X. tropicalis | naglu | CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). 3rd of 3 X.tropicalis mutant lines. Germ ... | NXR |
| Xtr.eomesem2Horb | X. tropicalis | eomes | 2nd CRISPR knockout of eomes (eomesodermin), carrying a 4bp deletion. Custom mutant generated by Ho... | |
| Xla.Tg(thibz:GFP)Demnx | X. laevis | fluorescent transgenic X. laevis embryos bearing a TH/bZIP-eGFP construct, used in toxicology labs t... | ||
| Xla.Tg(bcan.S:eGFP)LRBUH | X. laevis | Tg line created using New and Easy Xenopus Targeted integration (NEXTi), to introduce an enhanced gr... | ||
| Xla.Tg(sox2.L:eGFP)LRBUH | X. laevis | Tg line created using New and Easy Xenopus Targeted integration (NEXTi), to introduce an enhanced gr... | ||
| Xla.Tg(myod1.S:eGFP)LRBUH | X. laevis | Tg line created using New and Easy Xenopus Targeted integration (NEXTi), to introduce an enhanced gr... | ||
| Xla.Tg(krt12.2.L:eGFP)LRBUH | X. laevis | Tg line created using New and Easy Xenopus Targeted integration (NEXTi), to introduce an enhanced gr... | ||
| Xla.Tg (Xtr.mpo:eGFP)Kato | X. laevis | Transgenic X. laevis line expresses mpo, a myeloid cell marker, in the tadpole liver cortex, after ... | ||
| Xla.Tg (pax6: GFP; cmv: DsRED)Papal | X. laevis | pax6 driving green fluorescent protein (GFP) bred into an albino background. | ||
| Xla.wtTEFOR | X. laevis | Wild-type Xenopus laevis from TEFOR Paris-Saclay | ||
| Xla.albino | X. laevis | A generic strain of albino Xenopus laevis without more specific provenance. | ||
| Xla.Tg(hsp70:eGFP)Yumi | X. laevis | The hsp70-GFP F4 Tg Xenopus line containing enhanced GFP under the control of the hsp70 promoter, d... | ||
| Xla.Tg(Hsa.CSN1:beta-globin-eGFP)Umbhauer | X. laevis | CNS1 sequences were inserted upstream of a human β-globin basal promoter (− 37 to + 12) followed by ... | ||
| Xtr.slc2a7.tyr.hps6tmHUARC | X. tropicalis | hps6 slc2a7 tyr | triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7 | |
| Xtr.thratm,thrbtmShiyb | X. tropicalis | thra thrb | Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... |
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