Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.Et(CAGGS-SB10;cryga:RFP;CAGGS:GFP)6MMead | X. tropicalis | |||
| Xtr.Et(CAGGS-SB10;cryga:RFP;CAGGS:GFP)622EMead | X. tropicalis | |||
| Xtr.Tg(pax6:GFP;cryga:RFP;actc1:RFP)Grngr | X. tropicalis | Triple transgenic line, with coinjection of 3 constructs/cassettes: paired box 6 (pax6) driving GFP,... | ||
| Xtr.Tg(otx2:GFP)Kellr | X. tropicalis | Xenopus otx2 (orthodenticle homeobox 2) promoter driving GFP. | ||
| Xtr.Et(krt8:GAL4-VP16,UAS:GFP)Mead | X. tropicalis | Keratin 8 minimal promoter driving expression of GAL4VP16 fusion with UAS GFP reporter gene. Made u... | ||
| Xtr.Et(gata1:GFP)mysMead | X. tropicalis | GATA-1 promoter driving GFP, mister stripey (msy) integration into the apelin receptor gene. | ||
| Xtr.Tg(eef1a1:GFP)Krieg | X. tropicalis | Xenopus eukaryotic translation elongation factor 1 alpha 1 (eef1a1) promoter/enhancer driving GFP ex... | ||
| Xtr.Tg(CMV:memGFP)NXR | X. tropicalis | CMV promoter driving expression of membrane-bound GFP (mGFP). | ||
| Xtr.Et(CAGGS-SB10;cryga:RFP)8FMead | X. tropicalis | Double transgenic frogs harboring substrate transposon and transposase enzyme transgenes; outcross ... | ||
| Xtr.Et(CAGGS-SB10;cryga-RFP)7MMead | X. tropicalis | Double transgenic frogs harboring substrate transposon and transposase enzyme transgenes; outcross o... | ||
| Xtr.Et(CAGGS-SB10;cryga:RFP)7M8FMead | X. tropicalis | Double transgenic frogs harboring substrate transposon and transposase enzyme transgenes; outcross o... | ||
| Xtr.Et(CAGGS-SB10;cryga-RFP)622EMead | X. tropicalis | Double transgenic/Enhance trap (Et) line of frogs harboring substrate transposon and transposase enz... | ||
| Xla.Tg(CMV:hist2h2be-GFP;CMV:mRFPFlc | X. laevis | ross of CMV:hist2h2be-GFP line, in which CMV promoter drives GFP-tagged histone cluster 2, H2be, and... | ||
| Xla.Tg(CAG:SCAT3)Ueno | X. laevis | CAG promoter driving expression of SCAT3. Ubiquitous expression of Caspase 3 activation (apoptosis)... | ||
| Xla.Tg(Xtr.pax8:GFP)Ogino | X. laevis | paired box 8 (pax8) driving GFP. | ||
| Xla.Tg(tuba1a:MyrPalm-mRFP1)NXR | X. laevis | Xenopus tubulin alpha 1a (tuba1) promoter driving expression of membrane bound red fluorescent prote... | ||
| Xla.Tg(WntREs:dEGFP)Vlemx | X. laevis | Construct contains a synthetic Wnt-responsive promoter consisting of 7 copies of a TCF/LEF1 binding... | ||
| Xla.Tg(CMV:EGFP-synj2bp)Wtnbe | X. laevis | This transgenic Xenopus harbors an enhanced green fluorescent protein (EGFP) fused to the mitochondr... | ||
| Xtr.runx2emHorb | X. tropicalis | runx2 | CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab... | NXR |
| Xtr.wwoxemHorb | X. tropicalis | wwox | CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... | NXR |
| Xtr.amhem1NXR | X. tropicalis | amh | CRISPR knockout of amh (anti-Mullerian hormone). Germline transmission confirmed. Animals carry a +8... | NXR |
| Xtr.gfi1em1Horb | X. tropicalis | gfi1 | CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... | NXR |
| Xtr.sox2emHorb | X. tropicalis | sox2 | CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... | NXR |
| Xtr.otx2emHorb | X. tropicalis | otx2 | CRISPR knockout of otx2 (orthodenticle homeobox 2). Germ line transmission confirmed. Animals carry ... | |
| Xtr.kcnj11emHorb | X. tropicalis | kcnj8 | CRISPR knockout of kcnj11 (potassium channel, inwardly rectifying subfamily J, member 11). Germline ... | |
| Xtr.bcorem1Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 4bp delet... | |
| Xtr.nhlh1emHorb | X. tropicalis | nhlh1 | CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Germ line transmission confirmed. Mutation b... | |
| Xtr.wt1emHorb | X. tropicalis | wt1 | CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... | NXR |
| Xla.pkhd1emHorb | X. laevis | pkhd1.L | CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... | |
| Xla.pkd1em1Horb | X. laevis | pkd1.L | CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line... | |
| Xtr.foxb1em1Horb | X. tropicalis | foxb1 | CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme... | |
| Xtr.dtlemHorb | X. tropicalis | dtl | CRISPR knockout of dtl (denticleless E3 ubiquitin protein ligase homolog), Current mosaic founders, ... | |
| Xtr.myt1emHorb | X. tropicalis | myt1 | CRISPR knockout of myt1 (myelin transcription factor 1). Germ line transmission confirmed. gRNA gene... | |
| Xtr.eomesemHorb | X. tropicalis | eomes | CRISPR knockout of eomes (eomesodermin). Germ line transmission confirmed. gRNA targets exon 1 and 2... | |
| Xtr.arnt,arnt2emHorb | X. tropicalis | arnt | CRISPR knockout of arnt/arnt2 (aryl hydrocarbon receptor nuclear translocator), Current mosaic found... | |
| Xtr.shroom3emHorb | X. tropicalis | shroom3 | CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... | NXR |
| Xtr.zbtb21emHorb | X. tropicalis | zbtb21 | CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... | NXR |
| Xtr.tspan8em1Horb | X. tropicalis | tspan8 | CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... | NXR |
| Xtr.bace1emHorb | X. tropicalis | bace1 | CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1), Current mosaic founders, Not tested for ... | |
| Xtr.junbemHorb | X. tropicalis | junb | CRISPR knockout of junb (jun B proto-oncogene), Germ line transmission confirmed. Animals carry a 17... | |
| Xtr.mapk10emHorb | X. tropicalis | mapk10 | CRISPR knockout of mapk10 (mitogen-activated protein kinase 10), Germline transmission confirmed, Mu... | |
| Xtr.icam5emHorb | X. tropicalis | icam5 | CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line transmission confirmed. Cust... | NXR |
| Xtr.sox3emHorb | X. tropicalis | sox3 | CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... | NXR |
| Xla.Tg(tuba1a:deup1-eGFP)NXR | X. laevis | Tubulin promoter driving expression of deup1 fused to eGFP labeling both deuterosomes and centrioles... | ||
| Xtr.ezh2emHorb | X. tropicalis | ezh2 | CRISPR knockout of ezh2 (enhancer of zeste 2 polycomb repressive complex 2 subunit), Germ line trans... | |
| Xtr.tbx2emHorb | X. tropicalis | tbx2 | CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. | NXR |
| Xtr.zbtb14emHorb | X. tropicalis | zbtb14 | CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... | NXR |
| Xtr.notch4emHorb | X. tropicalis | notch4 | CRISPR knockout of notch4 in X. tropicalis. Confirmed germline transmission. Mutation characterized:... | |
| Xtr.tlx3em2Horb | X. tropicalis | tlx3 | CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... | |
| Xtr.runx1t1emHorb | X. tropicalis | runx1t1 | CRISPR knockout of runx1t1(RUNX1 partner transcriptional co-repressor 1) gene. Germ line transmissio... | NXR |
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