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Results 51 - 100 of 243 results

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Line Name Species Mutated Gene(s) Description Availability
Xtr.rxrbemHorb X. tropicalis rxrb CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a...
Xtr.rxraemNXR X. tropicalis rxra CRISPR knockout of rxra (retinoid X receptor alpha ). Germ line transmission confirmed. Animals carr...
Xtr.runx2emHorb X. tropicalis runx2 CRISPR knockout of runx2 (runt related transcription factor 2). Contact NXR to inquire about availab...
Xtr.runx1em3NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.runx1em2NXR X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.runx1em1Horb X. tropicalis runx1 CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani...
Xtr.runx1t1emHorb X. tropicalis runx1t1 CRISPR knockout of runx1t1(RUNX1 partner transcriptional co-repressor 1) gene. Germ line transmissio...
Xtr.rspo2emNXR X. tropicalis rspo2 CRISPR knockout of rspo2 (R-spondin 2 ). Germ line transmission confirmed. Contact NXR for more deta...
Xtr.ror2emNXR X. tropicalis ror2 CRISPR knockout of ror2 (receptor tyrosine kinase like orphan receptor 2). Germ line transmission no...
Xtr.ripply3emNXR X. tropicalis ripply3 CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ line transmission not yet confirmed....
Xtr.rfx6emNXR X. tropicalis rfx6 CRISPR KO of rfx6 (regulatory factor X6) in X. tropicalis. Germ line transmission not yet confirm...
Xtr.rflciiemNXR X. tropicalis rflcii CRISPR KO of rflcii ( relaxin family locus C type II ) in X tropicalis. Germ line transmission not y...
Xtr.raxmGrngr X. tropicalis rax This mutant line was generated in an ENU screen from the Grainger lab by TILLING (Targeting Induced ...
Xtr.prph2emHorb X. tropicalis prph2 CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germ line transmissi...
Xtr.pqbp1emNXR X. tropicalis pqbp1 CRISPR KO of pqbp1 (polyglutamine binding protein 1) in X tropicalis. Germ line transmission confirm...
Xtr.pou4f1emNXR X. tropicalis pou4f1 CRISPR knockout of pou4f1 (POU class 4 homeobox 1) in X. tropicalis. germ line transmission confirme...
Xtr.pou4f1em1NXR X. tropicalis pou4f1 CRISPR knockout of pou4f1 (POU class 4 homeobox 1) in X. tropicalis. germ line transmission confirme...
Xtr.pou3f4emHorb X. tropicalis pou3f4 CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline...
Xtr.pnhdemNXR X. tropicalis pnhd CRISPR knockout of pnhd (pinhead) in X tropicalis. germ line transmission confirmed. Mutation is a ...
Xtr.plekhg5emNXR X. tropicalis plekhg5 CRISPR knockout of plekhg5 (pleckstrin homology and RhoGEF domain containing G5 ) Germ line transmis...
Xtr.pigpemNXR X. tropicalis pigp CRISPR knockout of pigp (phosphatidylinositol glycan anchor biosynthesis class P )in X tropicalis. G...
Xtr.petmZimml X. tropicalis unknown Homozygous mutants are completely paralyzed with no heartbeat.
Xtr.otx2emHorb X. tropicalis otx2 CRISPR knockout of otx2 (orthodenticle homeobox 2). Germ line transmission confirmed. Animals carry ...
Xtr.olig4emHorb X. tropicalis olig4 CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test...
Xtr.olig3emNXR X. tropicalis olig3 CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) in X. tropicalis. Current mosaic ...
Xtr.olig2emHorb X. tropicalis olig2 CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. tropicalis. Confirme...
Xtr.oc90mZimml X. tropicalis oc90 Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. ...
Xtr.nr2f2emNXR X. tropicalis nr2f2 CRISPR knockout fo nr2f2 (nuclear receptor subfamily 2 group F member 2 ). Germ line transmission co...
Xtr.npntinsZimml X. tropicalis npnt Nephronectin insertional mutation (probably null). Insertion of Tg(nkx2.5:GFP) transgene between 3rd...
Xtr.notch4emHorb X. tropicalis notch4 CRISPR knockout of notch4 in X. tropicalis. Confirmed germline transmission. Mutation characterized:...
Xtr.nhlh1emHorb X. tropicalis nhlh1 CRISPR knockout of nhlh1 (nescient helix-loop-helix 1). Germ line transmission confirmed. Mutation b...
Xtr.nagluem2NXR X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals...
Xtr.nagluem1NXR X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals...
Xtr.naa20emNXR X. tropicalis naa20 CRISPR knockout fo naa20 (N(alpha)-acetyltransferase 20, NatB catalytic subunit ). Germ line transmi...
Xtr.myt1emHorb X. tropicalis myt1 CRISPR knockout of myt1 (myelin transcription factor 1). Germ line transmission confirmed. gRNA gene...
Xtr.myh6mZimml X. tropicalis myh6 Mutation affecting cardiac function identified in the Mill Hill screen of ENU-induced mutations. Non...
Xtr.myf6emNXR X. tropicalis myf6 TALENS knockout of myf6 (myogenic factor 6) in X tropicalis. Germ line transmission not yet confirme...
Xtr.mtnr1aemNXR X. tropicalis mtnr1a CRISPR knock out of mtnr1a (melatonin receptor 1A ) in X. tropicalis. germ line transmission confirm... NXR
Xtr.msx1emNXR X. tropicalis msx1 CRISPR knockout of msx1 (msh homeobox 1) in X. tropicalis. Custom line generated for Veenstra Lab. G...
Xtr.mlomZimml X. tropicalis unknown Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. Map...
Xtr.mitfemHorb X. tropicalis mitf CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes...
Xtr.meis1emNXR X. tropicalis meis1 CRISPR knockout of meis1 (meis homeobox 1). F0 growing, germline transmission not yet confirmed.
Xtr.mcidasemNXR X. tropicalis mcidas CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot...
Xtr.mapk10emHorb X. tropicalis mapk10 CRISPR knockout of mapk10 (mitogen-activated protein kinase 10), Germline transmission confirmed, Mu...
Xtr.map3k1emNXR X. tropicalis map3k1 CRISPR knockout of map3k1 (mitogen-activated protein kinase kinase kinase 1). Germ line transmission...
Xtr.map3k13emHorb X. tropicalis map3k13 CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t...
Xtr.mammZimml X. tropicalis unknown Mutation affecting cardiac function identified in a screen for ENU-induced mutations at Mill Hill
Xtr.lmnaemHorb X. tropicalis lmna CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Mutants carry a 14 bp deletion ...
Xtr.lepemNXR X. tropicalis lep CRISPR knockout of lep (leptin). Germ line transmission confirmed. F1s established. Animals carry a ...
Xtr.lepremNXR X. tropicalis lepr CRSIPR knockout of lepr (leptin receptor). Germ line transmission not yet confirmed. F0 founders. Co...

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