Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.gtpbp2emNXR | X. tropicalis | gtpbp2 | CRISPR knockout of gtpbp2 (GTP binding protein 2 ). Germ line transmission confirmed. Mutants carry ... | NXR |
| Xtr.gfi1em3Horb | X. tropicalis | gfi1 | CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... | |
| Xtr.gfi1em2Horb | X. tropicalis | gfi1 | CRISPR knockout of gfi1 (growth factor independent 1 transcription repressor). Germ line transmissio... | NXR |
| Xtr.fuzemNXR | X. tropicalis | fuz | CRAIPR knockout of fuz ( fuzzy planar cell polarity protein). Germ line transmission not yet confirm... | |
| Xtr.foxp3emNXR | X. tropicalis | foxp3 | CRISPR knockout of foxp3 (forkhead box P3). Germ line transmission confirmed. Animals carry a 1 bp d... | |
| Xtr.foxp2emNXR | X. tropicalis | foxp2 | CRISPR knockout of foxp2 (forkhead box P2). Germ line transmission not yet confirmed. Mutation not ... | |
| Xtr.foxl2em1NXR | X. tropicalis | foxl2 | CRISPR knockout of foxl2 (forkhead box L2). Germline transmission confirmed. Mosaic founders and F1s... | |
| Xtr.foxc2em2Horb | X. tropicalis | foxc2 | CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Custom mutant generated... | |
| Xtr.foxd3emNXR | X. tropicalis | foxd3 | CRISPR knockout of foxd3 (forkhead box D3). Germ line transmission confirmed. Mutation is a 5bp dele... | |
| Xtr.eya1em1NXR | X. tropicalis | eya1 | CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... | |
| Xtr.eya1emNXR | X. tropicalis | eya1 | CRISPR knockout of eya1 (EYA transcriptional coactivator and phosphatase 1). Germline transmission ... | |
| Xla.dzip1emNXR | X. laevis | dzip1.L | CRISPR knockout of dzip1 (Z interacting zinc finger protein 1). Germ line transmission not yet confi... | NXR |
| Xla.xdm-wemNXR | X. laevis | dm-w.L | CRISPR knock out of xdm-w (doublesex and mab3 related transcription factor W ). Germ Line transmissi... | |
| Xla.dmrt1em3NXR | X. laevis | dmrt1.S | CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1 ). Custom mutant line... | |
| Xla.dmrt1em2NXR | X. laevis | dmrt1.S | CRISPR knockout of dmrt1.S (doublesex and mab-3 related transcription factor 1). Germline transmissi... | |
| Xla.dmrt1em1NXR | X. laevis | dmrt1.L | CRISPR knockout of dmrt1.L (doublesex and mab-3 related transcription factor 1 ). Germ line transmis... | |
| Xtr.dmrt1emNXR | X. tropicalis | dmrt1 | Xtropicalis CRISPR knockout of dmrt1 (doublesex and mab-3 related transcription factor 1). Germ line... | NXR |
| Xtr.cybbemHorb | X. tropicalis | cybb | CRISPR knockout of cybb (cytochrome b-245, beta polypeptide). Germ line transmission not confirmed. ... | NXR |
| Xtr.csnk1g2emNXR | X. tropicalis | csnk1g2 | CRISPR knockout of csnk1g2 (casein kinase 1 gamma 2). Germ line transmission confirmed. Mutation is ... | NXR |
| Xla.csf3remNXR | X. laevis | csf3r.L | CRISPR knockout of csf3r (colony stimulating factor 3 receptor ). Germ line transmission not yet con... | NXR |
| Xtr.cby1emNXR | X. tropicalis | cby1 | TALEN knockout of cby1 (chibby homolog 1). Germ line transmission not confirmed. Mutation not charac... | NXR |
| Xtr.celf3emNXR | X. tropicalis | celf3 | CRISPR knock out of celf3 (CUGBP, Elav-like family member 3). Germ line transmission not yet confirm... | NXR |
| Xla.ccdc78emNXR | X. laevis | ccdc78.S | CRISPR knockout of ccdc78 (coiled-coil domain containing 78). Germ line transmission confirmed. Muta... | |
| Xtr.cacna1hem2NXR | X. tropicalis | cacna1h | CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... | NXR |
| Xtr.cacna1hem1NXR | X. tropicalis | cacna1h | CRISPR knockout of cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Mutation ... | NXR |
| Xtr.bicc1em1NXR | X. tropicalis | bicc1 | CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed... | NXR |
| Xtr.bcorem4Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 11bp dele... | |
| Xtr.bcorem3Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 5bp delet... | |
| Xtr.bcorem2Horb | X. tropicalis | bcor | CRISPR knockout of bcor (BCL6 corepressor). Germline transmission confirmed. Mutation is a 1bp delet... | NXR |
| Xla.arntlemNXR | X. laevis | bmal1.L | CRISPR knockout of arntl (arbon receptor nuclear translocator like). Germline transmission confirme... | |
| Xla.arem2NXR | X. laevis | ar.L | CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 19bp deletion in ar.L (GAGTGTG... | NXR |
| Xla.ar em1NXR | X. laevis | ar.L | CRISPR mutation of ar (androgen receptor). Mutation is confirmed as a 13bp deletion in ar.L ( AGTGTG... | |
| Xtr.amhr2emNXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Confirmed germline transmission... | |
| Xtr.amhem3NXR | X. tropicalis | amh | 3rd of 3 different X. tropicalis CRISPR knockout lines targeting amh (anti-Mullerian hormone ) dev... | NXR |
| Xtr.amhem2NXR | X. tropicalis | amh | 2nd of 3 different X. tropicalis CRISPR knockout lines targeting amh (anti-Mullerian hormone ) deve... | NXR |
| Xtr.aif1lem2Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | NXR |
| Xla.ahremNXR | X. laevis | ahr.L | Custom generated mutant made by NXR. Germ line transmission not yet confirmed. Contact NXR for detai... | |
| Xtr.ahrem2NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. mutation: 7bp deleti... | NXR |
| Xtr.ahrem1NXR | X. tropicalis | ahr | TALEN generated mutant line, made by the NXR. Germ line transmission confirmed. ,+2bp mutation: CCAT... | |
| Xla.adam13emNXR | X. laevis | CRISPR knockout of adam13 (ADAM metallopeptidase domain 13 ). Confirmed germline transmission. Anima... | ||
| Xla.Tg(prrx1:CreER;CAGGs:lp-Cherry)Etnka | X. laevis | A stable double transgenic frog line that allows conditional labeling and tracing of limb connectiv... | ||
| Xla.Tg(rho:hsa.rhodel) | X. laevis | Line with a human mutant form of rhodopsin with a Glutamine to termination substitution, under the X... | ||
| Xla.Tg(rho:Hsa.rhosub_T4K) | X. laevis | Line with a human mutant form of rhodopsin with a Threonine to Lysine substitution, under the X.laev... | ||
| Xla.Tg(rho:Hsa.rhosub_T17M) | X. laevis | Line with a human mutant form of rhodopsin with a Threonine to Methionine substitution, under the X.... | ||
| Xla.Tg(rho:hsa.rhosub_P23H) | X. laevis | Line with a human mutant form of rhodopsin with a Proline to Histidine substitution, which leads to ... | ||
| Xtr.thratmShiyb | X. tropicalis | thra | This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... | |
| Xla.kcptmFlc | X. laevis | kcp.L | One-cell stage Xenopus Xla.Tg(Cardiac-actin:GFP)Mohun embryos were microinjected with 1 ng TALEN mRN... | |
| Xtr.tp53em_del1/em_del2_Vlemx | X. tropicalis | tp53 | Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... | |
| Xla.hps4m | X. laevis | hps4.L | This periodic albino mutant of Xenopus laevis is a recessive mutant. Fukazawa et al 2020 showed that... | |
| Xla.Tg(Dre.gfap:mCherry-NTR)Larra | X. laevis | This transgenic line allows selective cell ablation in the CNS. NTR, Nitroreductase. Transgene was i... |
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