Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xla.pkd2emHorb | X. laevis | pkd2.L | CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Confirmed germ... | |
| Xla.pcntemHorb | X. laevis | pcnt.L | CRISPR knockout of pcnt (pericentrin ). Confirmed germline transmission. Custom mutant generated by ... | |
| Xla.pax7emHorb | X. laevis | pax7.L | CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a 4bp 9 bp o... | NXR |
| Xla.pax3emHorb | X. laevis | pax3.L | CRISPR knockout of pax3 (paired box 3). Germ line transmission confirmed. animals carry a 11bp delet... | |
| Xla.olig3emHorb | X. laevis | olig3.S | CRISPR knockout of olig3 (oligodendrocyte transcription factor 3) ( olig3.S in Xlaevis). Current mos... | |
| Xtr.hpse2emHorb | X. tropicalis | hpse2 | CRISPR knockout of hpse2 (heparanase 2 (inactive)). Confirmed germline transmission. Custom mutant g... | NXR |
| Xtr.glis3emHorb | X. tropicalis | glis3 | CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Custom mutant... | NXR |
| Xtr.frzb,frzb2emHorb | X. tropicalis | frzb2 | double CRISPR knockout of frzb (frizzled related protein ) and frzb2 (frizzled related protein 2). C... | |
| Xtr.foxc2em1Horb | X. tropicalis | foxc2 | CRISPR knockout of foxc2 (forkhead box C2). Confirmed germline transmission. Animals carry a 1 bp de... | |
| Xtr.erfemHorb | X. tropicalis | erf | CRISPR knockout of erf (ETS2 repressor factor). Confirmed germline transmission. Custom mutant gene... | |
| Xtr.gdf1em1Horb | X. tropicalis | gdf1 | CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... | NXR |
| Xtr.ascl1emHorb | X. tropicalis | ascl1 | CRISPR knockout of ascl1(achaete-scute family bHLH transcription factor 1). Confirmed germline trans... | |
| Xtr.aif1lem1Horb | X. tropicalis | aif1l | CRISPR knockout of aif1l (allograft inflammatory factor 1-like). Confirmed germline transmission. Cu... | |
| Xtr.tlx3em1Horb | X. tropicalis | tlx3 | CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... | |
| Xtr.map3k13emHorb | X. tropicalis | map3k13 | CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germline t... | |
| Xtr.rxrgemHorb | X. tropicalis | rxrg | Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... | NXR |
| Xtr.rxrbemHorb | X. tropicalis | rxrb | CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a... | NXR |
| Xtr.runx1em1Horb | X. tropicalis | runx1 | CRISPR knockout of runx1(runt related transcription factor 1). Germ line transmission confirmed. Ani... | NXR |
| Xtr.prph2emHorb | X. tropicalis | prph2 | CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Confirmed germ line transmissi... | NXR |
| Xtr.pou3f4emHorb | X. tropicalis | pou3f4 | CRISPR knockout of pou3f4 (POU class 3 homeobox 4). Current mosaic founders, not tested for germline... | |
| Xtr.olig4emHorb | X. tropicalis | olig4 | CRISPR knockout of olig4 (oligodendrocyte transcription factor 4). Current mosaic founders, not test... | |
| Xtr.olig2emHorb | X. tropicalis | olig2 | CRISPR knockout of olig2 (oligodendrocyte lineage transcription factor 2) in X. tropicalis. Confirme... | NXR |
| Xtr.mitfemHorb | X. tropicalis | mitf | CRISPR knockout of mitf (melanocyte inducing transcription factor). Current mosaic founders, not tes... | |
| Xtr.lmnaemHorb | X. tropicalis | lmna | CRISPR knockout of lmna (lamin A/C).Confirmed germline transmission. Mutants carry a 14 bp deletion ... | |
| Xtr.insm2emHorb | X. tropicalis | insm2 | CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Custom mutant g... | |
| Xtr.hps6mGrngr | X. tropicalis | hps6 | No Privacy (NOP) embryos have a 10-bp deletion in the hps6 gene (a region from 468 to 477 counted fr... | |
| Xla.Tg(nkx2-5:GFP)Mohun | X. laevis | 8kb promoter of X. laevis NK2 homeobox 5 gene driving GFP | ||
| Xla.Tg(myl2:eGFP)Mohun | X. laevis | ~3kb myosin light chain (myl2, also known as xmlc2/mlc2) promoter driving enhanced GFP (eGFP) expres... | ||
| Xla.Tg(CMV:H3K9ac-mintbody)Ueno | X. laevis | CMV promoter driving expression of of the epigenetic sensor, H3K9ac-mintbody (modification-specific ... | ||
| Xla.Tg(tubb2b:ChIEF;Rno.elas:GFP)NXR | X. laevis | Xenopus neural (NBT/tubb2b) driving expression of blue light photoinducible channel rhodopsin (ChIEF... | ||
| Xla.Tg(ins:memGFP,cryga:mCherry)NXR | X. laevis | X. laevis 5kb insulin (ins) promoter driving membrane bound GFP (mGFP) expression; gamma crystallin ... | ||
| Xla.Tg(gata1:GFP)Mead | X. laevis | Xenopus GATA-1 (gata1) promoter and first intron, driving expression of GFP | ||
| Xla.Tg(tubb2b:GCaMP6s;Rno.elas:GFP)NXR | X. laevis | neural beta tubulin ( tubb2b) driving GCaMP6s, a genetically encoded calcium indicator created from ... | ||
| Xla.Tg(rho:eGFP-atp1a3)Baker | X. laevis | Xenopus rhodopsin (rho) promoter driving expression of eGFP tagged neuronal alpha-3 isoform of the N... | ||
| Xla.Tg(eef1a1:GFP;cryga:GFP)Krieg | X. laevis | Xenopus eukaryotic translation elongation factor 1 alpha 1 (eef1a1) promoter/enhancer driving GFP ex... | ||
| Xla.Tg(CMV-vsFP2.42_SRL)NXR | X. laevis | vsFP is a voltage sensitive Fluorescent Potein. vsFP enables optical recordings at high spatial reso... | ||
| Xla.Tg(CMV:GFP)Murray | X. laevis | CMV promoter driving GFP expression | ||
| Xla.Tg(CMV:VSFP-Butterfly1.2)NXR | X. laevis | vsFP is a voltage-sensitive Fluorescent Protein. vsFP-Butterfly 1.2 enables optical recordings at hi... | ||
| Xla.Tg(CMV:Aequorin,GFP)NXR | X. laevis | CMV promoter driving expression of Aequorin and GFP. Aequorin is a Ca2+-dependent bioluminescence ph... | ||
| Xla.Tg(CMV:memGFP;cryga:mCherry)NXR | X. laevis | CMV promoter driving expression of membrane bound GFP, and a gamma-crystallin (cryga) driving expres... | ||
| Xla.Tg(CMV:cetn4-RFP)NXR | X. laevis | CMV promoter driving expression of centrin 4 (cetn4) fused with RFP. Custom transgenic generatedÃÂ ... | ||
| Xla.Tg(Dre.cdh17:eGFP)NXR | X. laevis | Zebrafish (Dre) Li-cadherin (cdh17) driving eGFP expression. Custom transgenic generated by the NXR ... | ||
| Xla.Tg(CAG:KikGR)Flc | X. laevis | CAG promoter driving green-to-red photoconvertible fluorescent protein, Kikume Green-Red (KikGR) | ||
| Xla.Tg(CAG:GFP)Mead | X. laevis | |||
| Xla.Tg(CMV-Brainbow1.0R)NXR | X. laevis | In Brainbow transgenes, Cre/lox recombination is used to create a stochastic choice of expression be... | ||
| Xla.Tg(CMV:Brainbow1.0L)NXR | X. laevis | To generate original lines of mice expressing Brainbow in neurons, the Brainbow-1 and Brainbow-2 con... | ||
| Xla.Tg(CMV:Brainbow1.0H)NXR | X. laevis | In original discovery, Brainbow-1 and Brainbow-2 constructs were placed under the control of regulat... | ||
| Xla.Tg(CMV:hist2h2be-RFP;cryga:VenusNXR | X. laevis | CMV promoterdriving Xenopus Histone 2B (xH2B, or hist2h2b)- RFP. fusion, with crystallin gamma A dri... | ||
| Xla.Tg(Xtr.tbxt:Katushka;cryga:Venus)EXRC | X. laevis | A 3856bp X. tropicalis (Xtr) Brachyury (tbxt) promoter driving expression of Katushka (TurboFP-C);... | ||
| Xla.Tg(pax3:GFP)EXRC | X. laevis | 2916bp X. laevis pax3 promoter driving expression of GFP; Pax3 promoter from Mayor Lab ( from Mauri... |
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