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Results 1 - 50 of 263 results

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Line Name Species Mutated Gene(s) Description Availability
Xtr.icam5em2Horb X. tropicalis icam5 2nd Xtropicalis line with CRISPR knockout of icam5 (intercellular adhesion molecule 5), Germ line tr... NXR
Xtr.hs6st1emNXR X. tropicalis hs6st1 CRISPR knockout of hs6st1 (heparan sulfate 6-O-sulfotransferase 1) gene. Mutation not yet characteri... NXR
Xtr.gdf1em3Horb X. tropicalis gdf1 CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom m... NXR
Xla.dmrt1em4NXR X. laevis dmrt1.L dmrt1.S Double X. levis CRISPR knockout line, targeting both dmrt1.S and dmrt1.L (doublesex and mab-3 relat... NXR
Xtr.cbsemNXR X. tropicalis cbs Custom CRISPR generated by NXR, targeting the cbs (cystathionine-beta-synthase) gene, NXR
Xtr.snai2em3NXR X. tropicalis snai2 3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... NXR
Xtr.snai2 em2NXR X. tropicalis snai2 CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... NXR
Xtr.sobp[em2NXR] X. tropicalis sobp 2nd of 2 CRISPR knockout of sobp (sine oculis binding protein homolog ) X. tropicalis lines held by ... NXR
Xtr.syngap1 emNXR X. tropicalis syngap1 CRISPR line targeting syngap1 (). Not screened for mutation or germ line transmission yet. Contact t... NXR
Xla.tcf3emNXR X. laevis tcf3.L X. laevis CRISPR line targeting tcf3.L (transcription factor 3). Line in development. Contact NXR f... NXR
Xla.tbx21emNXR X. laevis tbx21.L tbx21.S double CRISPR KO line targeting tbx21.L and tbx21.S in X. laevis. germ line transmission snd mutatio... NXR
Xla.tap2emNXR X. laevis tap2.L tap2.S X. laevis CRISPR line targeting tap2 (transporter 2, ATP-binding cassette, sub-family B (MDR/TAP), a... NXR
Xla.tap1emNXR X. laevis tap1.L X. laevis CRISPR line targeting tap1 (transporter 1, ATP-binding cassette, sub-family B (MDR/TAP), a... NXR
Xla.tracemHorb X. laevis trac.S X. laevis CRISPR line targeting trac.S (T cell receptor alpha constant), a gene associated with immu... NXR
Xla.velo1emNXR X. laevis velo1.L X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized . Germ lin... NXR
Xla.wnt3em2NXR X. laevis wnt3.L X. laevis CRISPR line targeting wnt3.L (Wnt family member 3). Germ line transmission not yet confirm...
Xla.wnt3em1NXR X. laevis wnt3.S X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission not yet confirm... NXR
Xtr.wnt3em1NXR X. tropicalis wnt3 CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed, mutation... NXR
Xtr.xbp1em2NXR X. tropicalis xbp1 2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1, a gene assocaited with Major Affec... NXR
Xtr.shroom3em2Horb X. tropicalis shroom3 CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... NXR
Xtr.ripply3em2NXR X. tropicalis ripply3 2nd of 2 ripply3 lines at the NXR, CRISPR KO of ripply3 (ripply transcriptional repressor 3). Germ l... NXR
Xtr.prph2em2Horb X. tropicalis prph2 2nd X. tropicalis line with CRISPR knockout of prph2 (peripherin 2 (retinal degeneration, slow)). Co... NXR
Xtr.pou4f1em2NXR X. tropicalis pou4f1 Custom CRISPR Xtropicalis line carrying a single 1bp insertion in pou4f1 (POU class 4 homeobox 1) ge... NXR
Xla.pkhd1em3Horb X. laevis pkhd1.L 3rd of 3 X. laevis CRISPR lines for pkhd1 (ciliary IPT domain containing fibrocystin/polyductin) gen... NXR
Xla.pkhd1em2Horb X. laevis pkhd1.L CRISPR knockout of pkhd1 (PKHD1, fibrocystin/polyductin), Germ line transmission confirmed. Animals ... NXR
Xla.pax7em3Horb X. laevis pax7.L pax7.S 3rd Xlaevis pax7 mutant line at the NXR. CRISPR knockout of pax7 (paired box 7). Germ line transmiss... NXR
Xla.pax7em2Horb X. laevis pax7.L pax7.S CRISPR knockout of pax7 (paired box ). Germ line transmission confirmed. Animals carry a -22bp dele... NXR
Xtr.notch4 em2Horb X. tropicalis notch4 the 2nd of 2 notch4 lines in X. tropicalis being bred by Horb lab. Contact NXR for details. NXR
Xtr.nagluem3NXR) X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). 3rd of 3 X.tropicalis mutant lines. Germ ... NXR
Xtr.eomesem2Horb X. tropicalis eomes 2nd CRISPR knockout of eomes (eomesodermin), carrying a 4bp deletion. Custom mutant generated by Ho...
Xtr.slc2a7.tyr.hps6tmHUARC X. tropicalis hps6 slc2a7 tyr triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7
Xtr.thratm,thrbtmShiyb X. tropicalis thra thrb Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S...
Xtr.tyremOchi X. tropicalis tyr An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... NBRP
Xtr.tyremKtsz X. tropicalis tyr An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... NBRP
Xtr.hps6emOgino X. tropicalis hps6 CRISPR/Cas9-mediated targeted mutation in hsp6, a gene resonsible for X. tropicalis no privacy (nop)... NBRP
Xla.pkd1em3Horb X. laevis pkd1.L CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line ...
Xla.pkd1em2Horb X. laevis pkd1.L CRISPR knockout of pkd1 (polycystin 1, transient receptor potential channel interacting). Germ line ... NXR
Xla.prkdcem2NXR X. laevis prkdc.L CRISPR KO of prkdc (protein kinase, DNA-activated, catalytic subunit ). Germ line transmission confi... NXR
Xtr.bicc1em2NXR X. tropicalis bicc1 CRISPR mutant of bicc1 (BicC family RNA binding protein 1). Germline transmission has been confirmed...
Xtr.staremNXR X. tropicalis star CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con...
Xtr.foxb1em2Horb X. tropicalis foxb1 CRISPR knockout of foxb1 (forkhead box B1 ), Current mosaic founders, germline transmission confirme...
Xtr.gdf1em2Horb X. tropicalis gdf1 CRISPR knockout of gdf1 (growth differentiation factor 1). Confirmed germline transmission. Custom ... NXR
Xtr.acsl1emNXR X. tropicalis acsl1 CRISPR knockout of acsl1 (acyl-CoA synthetase long chain family member 1). Germ line transmission co...
Xtr.nagluem2NXR X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase). Germ line transmission confirmed. Animals... NXR
Xtr.nagluem1NXR X. tropicalis naglu CRISPR knockout of naglu (N-acetyl-alpha-glucosaminidase) gene. Germ line transmission confirmed. An... NXR
Xtr.lamp2em2NXR X. tropicalis lamp2 CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme...
Xtr.lamp2em1NXR X. tropicalis lamp2 CRISPR knockout of lamp2 (lysosomal associated membrane protein 2 ). Germ line transmission confirme...
Xla.rag2emNXR X. laevis rag2.L CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carr... NXR
Xtr.meis1emNXR X. tropicalis meis1 CRISPR knockout of meis1 (meis homeobox 1). F0 growing, germline transmission not yet confirmed.
Xla.rykemNXR X. laevis ryk.S CRISPR knockout of ryk.S (receptor like tyrosine kinase S homeolog). Germline transmission not yet c... NXR

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