Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xla.trilem2NXR | X. laevis | tril.L tril.S | CRISPR knockout of tril (TLR4 interactor with leucine-rich repeats). Germline transmission not yet c... | NXR |
| Xla.tracem2Horb | X. laevis | trac.L trac.S | CRISPR knockout of trac (T cell receptor alpha constant). Guide targeting S alloallele was injected ... | NXR |
| Xla.rbp3emHorb | X. laevis | rbp3.L | CRISPR of rbp3 (retinol binding protein 3). Germline transmission not yet confirmed. Contact the NXR... | NXR |
| Xtr.ebf3emHorb | X. tropicalis | ebf3 | CRISPR knockout of ebf3 (EBF transcription factor 3). Germline transmission not yet confirmed. Conta... | NXR |
| Xla.ebf3emHorb | X. laevis | ebf3.S | CRISPR knockout of ebf3 (EBF transcription factor 3). Germline transmission not yet confirmed. Conta... | NXR |
| Xla.clec4eemHorb | X. laevis | clec4e.S | CRISPR knockout of clec4e (C-type lectin domain family 4 member E). Germline transmission not yet co... | NXR |
| Xtr.clec4eemHorb | X. tropicalis | clec4e | CRISPR knockout of clec4e (C-type lectin domain family 4 member E). Germline transmission not yet co... | NXR |
| Xtr.zbtb21em2Horb | X. tropicalis | zbtb14 | CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Different sgRNA sequence from ... | NXR |
| Xtr.tlr2emHorb | X. tropicalis | tlr2 | CRISPR knockout in tlr2 (toll like receptor 2). Germline transmission not yet confirmed. Contact the... | NXR |
| Xla.cxcl8b.2em2Horb | X. laevis | cxcl8b.2.L | CRISPR knockout of cxcl8b (C-X-C motif chemokine ligand 8) and also known as il8b (interleukin-8). G... | NXR |
| Xla.hey1emHorb | X. laevis | hey1.L hey1.S | CRISPR knockout in hey1 (hes related family bHLH transcription factor with YRPW motif 1). Germline t... | NXR |
| Xtr.srd5a2em2NXR | X. tropicalis | srd5a2 | CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2). Confirmed germ line transmission. Animals c... | NXR |
| Xtr.rxrbem2Horb | X. tropicalis | rxrb | CRISPR knockout of rxrb (retinoid X receptor beta). Confirmed germline transmission. Animals carry a... | NXR |
| Xtr.rbp3emHorb | X. tropicalis | rbp3 | CRISPR knockout of rbp3 (retinol binding protein 3). Germline transmission not yet confirmed. Contac... | NXR |
| Xtr.rag1emHorb | X. tropicalis | rag1 | CRISPR knockout of rag1 (recombination activating gene 1). Germ line transmission not yet confirmed.... | NXR |
| Xtr.plekhg5em2NXR | X. tropicalis | plekhg5 | CRISPR knockout of plekhg5 (pleckstrin homology and RhoGEF domain containing G5 ) Germ line transmis... | NXR |
| Xtr.ntf3emHorb | X. tropicalis | ntf3 | CRISPR knockout of ntf3 (neurotrophin 3). Germline transmission not yet confirmed. Contact the NXR f... | NXR |
| Xtr.nrg1emHorb | X. tropicalis | nrg1 | CRISPR knockout of nrg1 (neuregulin 1). Germline transmission not yet confirmed. Contact the NXR for... | NXR |
| Xtr.myt1em2Horb | X. tropicalis | myt1 | CRISPR knockout of myt1 (myelin transcription factor 1). Germ line transmission confirmed. Animals c... | NXR |
| Xtr.mtnr1bemNXR | X. tropicalis | mtnr1b | CRISPR knockout of mtnr1b (melatonin receptor 1B). Confirmed germline transmission. Contact the NXR ... | |
| Xtr.meis1em2Horb | X. tropicalis | meis1 | CRISPR knockout of meis1 (meis homeobox 1). Germline transmission confirmed. Animals carry a 7 base ... | NXR |
| Xtr.mcidas em2NXR | X. tropicalis | mcidas | CRISPR knockout of mcidas (multiciliate differentiation and DNA synthesis associated cell cycle prot... | NXR |
| Xtr.map3k13em2Horb | X. tropicalis | map3k13 | CRISPR knockout of map3k13 (mitogen-activated protein kinase kinase kinase 13). Confirmed germ line ... | NXR |
| Xtr.lrrk2em3NXR | X. tropicalis | lrrk2 | CRISPR knockout of lrrk2 (leucine-rich repeat kinase 2 ). Germ line transmission confirmed. New line... | NXR |
| Xtr.lrrk2em2NXR | X. tropicalis | lrrk2 | CRISPR knockout of lrrk2 (leucine-rich repeat kinase 2 ). Germ line transmission confirmed. Animals ... | NXR |
| Xtr.lmnaem2Horb | X. tropicalis | lmna | CRISPR knockout of lmna (lamin A/C). Confirmed germline transmission. Mutants carry an 11 base pair ... | NXR |
| Xtr.leprem2NXR | X. tropicalis | lepr | CRSIPR knockout of lepr (leptin receptor). Germ line transmission confirmed. Animals carry a 26 base... | NXR |
| Xtr.lepem2NXR | X. tropicalis | lep | CRISPR knockout of lep (leptin). Germ line transmission confirmed. Animals carry an 10 base pair del... | NXR |
| Xtr.bhlhe22em2Horb | X. tropicalis | bhlhe22 | CRISPR knockout of bhlhe22 (basic helix-loop-helix family member e22), Germ line transmission confir... | NXR |
| Xtr.bace1em2Horb | X. tropicalis | bace1 | CRISPR knockout of bace1 (beta-site APP-cleaving enzyme 1). Germ line transmission confirmed. Animal... | NXR |
| Xtr.kcnj11em2Horb | X. tropicalis | kcnj11 | CRISPR knockout of kcnj11 (potassium channel, inwardly rectifying subfamily J, member 11). Germline ... | NXR |
| Xtr.irx3em2NXR | X. tropicalis | irx3 | CRISPR knockout of irx3 (iroquois homeobox 3). Custom mutant line generated for the Veenstra Lab. Ge... | NXR |
| Xtr.insm2em2Horb | X. tropicalis | insm2 | CRISPR knockout of insm2 (insulinoma-associated 2). Confirmed germline transmission. Animals carry a... | NXR |
| Xtr.invsemHorb | X. tropicalis | invs | CRISPR knockout of invs (inversin). Germline transmission not yet confirmed. Contact the NXR for mor... | NXR |
| Xtr.hey2emHorb | X. tropicalis | hey2 | CRISPR knockout of hey2 (hes related family bHLH transcription factor with YRPW motif 2). Germline t... | NXR |
| Xtr.hey1emHorb | X. tropicalis | hey1 | CRISPR knockout of hey1 (hes related family bHLH transcription factor with YRPW motif 1). Germline t... | NXR |
| Xtr.glis3em2Horb | X. tropicalis | glis3 | CRISPR knockout of glis3 (GLIS family zinc finger 3). Confirmed germline transmission. Animals carry... | NXR |
| Xtr.eya1em2NXR | X. tropicalis | eya1 | CRISPR knockout in eya1 (EYA transcriptional coactivator and phosphatase 1). Germ line transmission ... | NXR |
| Xtr.esr2emHorb | X. tropicalis | esr2 | CRISPR knockout in esr2 (estrogen receptor 2). Germline transmission not yet confirmed. Custom mutan... | NXR |
| Xtr.esr1emHorb | X. tropicalis | esr1 | CRISPR knockout in esr1 (estrogen receptor 1). Germline transmission not yet confirmed. Custom mutan... | NXR |
| Xtr.aremHorb | X. tropicalis | ar | CRISPR knockout in ar (androgen receptor). Germ line transmission not yet confirmed. Contact the NXR... | NXR |
| Xtr.amhr2em2NXR | X. tropicalis | amhr2 | CRISPR knockout of amhr2 (anti-Mullerian hormone receptor type II ). Germ line transmission not yet ... | NXR |
| Xla.ism1emHorb | X. laevis | ism1.L | CRISPR knockout in ism1.L (isthmin 1). Germline transmission not yet confirmed. Contact the NXR for ... | NXR |
| Xla.hey2emHorb | X. laevis | hey2.L | CRISPR knockout of hey2.L (hes related family bHLH transcription factor with YRPW motif 2). Germline... | NXR |
| Xla.fzd7emHorb | X. laevis | fzd7.L fzd7.S | CRISPR knockout of fzd7 (frizzled class receptor 7). Germline transmission not yet confirmed. Contac... | NXR |
| Xla.foxn1em3NXR | X. laevis | foxn1.S | CRISPR knockout of foxn1.S (forkhead box N1). Germ line transmission not yet confirmed. Contact NXR ... | NXR |
| Xla.esr1emHorb | X. laevis | esr1.L | CRISPR knock out in esr1 (estrogen receptor 1). Germline transmission not yet confirmed. Contact the... | NXR |
| Xla.acsl5em2NXR | X. laevis | acsl5.L | CRISPR knock out of acsl5 (acyl-CoA synthetase long chain family member 5 ). Germ line transmission ... | NXR |
| Xla.wnt11b+/- | X. laevis | wnt11b.L | Heterozygote offspring from a cross between a homozygous wnt11b{-/-} father and wildtype mother. Als... | |
| Xla.wnt11b-/- | X. laevis | wnt11b.L | Homozygote offspring from a cross between a homozygous wnt11b{-/-} mother and father. Also described... |
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