Search Lines and Strains
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| Line Name | Species | Mutated Gene(s) | Description | Availability |
| Xtr.mhc1aemHorb | X. tropicalis | mhc1a | CRISPR knockout of mhc1a (major histocompatibility complex class I antigen). Germline transmission n... | NXR |
| Xla.mas1emHorb | X. laevis | mas1.L | CRISPR knockout of mas1 (MAS1 proto-oncogene, G protein-coupled receptor). Germline transmission not... | NXR |
| Xtr.esr1em2Horb | X. tropicalis | esr1 | CRISPR knockout in esr1 (estrogen receptor 1). Germline transmission confirmed. Custom mutant genera... | NXR |
| Xla.csf1emHorb | X. laevis | csf1.S | CRISPR knockout of csf1 (colony stimulating factor-1). Germline transmission not yet confirmed. Cont... | NXR |
| Xtr.csf1emHorb | X. tropicalis | csf1 | CRISPR knockout of csf1 (colony stimulating factor-1). Germline transmission not yet confirmed. Cont... | NXR |
| Xla.dzip1em2NXR | X. laevis | dzip1.L | CRISPR knockout of dzip1 (Z interacting zinc finger protein 1). Germ line transmission confirmed. An... | NXR |
| Xtr.irf1emHorb | X. tropicalis | irf1 | CRISPR knockout of irf1 (interferon regulatory factor 1). Germline transmission not yet confirmed. C... | NXR |
| Xtr.nr4a1emHorb | X. tropicalis | nr4a1 | CRISPR knockout targeting nr4a1 (nuclear receptor subfamily 4 group A member 1). Germline transmissi... | NXR |
| Xtr.ror2em2NXR | X. tropicalis | ror2 | CRISPR knockout of ror2 (receptor tyrosine kinase like orphan receptor 2). Germ line transmission co... | NXR |
| Xla.wnt3em3NXR | X. laevis | wnt3.S | X. laevis CRISPR line targeting wnt3.S (Wnt family member 3). Germ line transmission confirmed, Anim... | NXR |
| Xtr.wnt3em2NXR | X. tropicalis | wnt3 | CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission confirmed. Animals carry a ... | NXR |
| Xla.ebf3em2Horb | X. laevis | ebf3.S | CRISPR knockout of ebf3 (EBF transcription factor 3). Germline transmission confirmed. Animals carry... | NXR |
| Xtr.adam9emHorb | X. tropicalis | adam9 | CRISPR knockout of adam9 (ADAM metallopeptidase domain 9). Germline transmission not yet confirmed. ... | NXR |
| Xtr.dot1lemShiyb | X. tropicalis | dot1l | TALEN generated mutation within the methyltransferase domain of X. tropicalis dot1l (DOT1-like histo... | |
| Xla.ifih1emHorb | X. laevis | ifih1.L | CRISPR knockout of ifih1 (interferon induced, with helicase C domain 1). Germline transmission not y... | NXR |
| Xtr.rflciiem2NXR | X. tropicalis | insl3 | CRISPR knockout of rflcii (relaxin family locus C type II ) in X tropicalis. Germ line transmission ... | NXR |
| Xla.esr1em3Horb | X. laevis | esr1.L esr1.S | Double knockout of esr1.L&S (estrogen receptor 1). Germline transmission not yet confirmed. Contact ... | NXR |
| Xla.esr1,esr2emHorb | X. laevis | esr1.L esr1.S esr2.L | Triple CRISPR knockout of esr1.L&S and esr2.L (estrogen receptor 1 and estrogen receptor 2). Germlin... | NXR |
| Xla.esr1em2Horb | X. laevis | esr1.S | CRISPR knock out in esr1.S (estrogen receptor 1). Germline transmission not yet confirmed. Contact t... | NXR |
| Xla.velo1em2NXR | X. laevis | velo1.L | X. laevis CRISPR line targeting velo1.L (velo1 protein). Mutation not yet characterized. Germ line t... | NXR |
| Xtr.rag1em2Horb | X. tropicalis | rag1 | CRISPR knockout of rag1 (recombination activating gene 1). Germ line transmission confirmed. Animals... | NXR |
| Xtr.irx2em2NXR | X. tropicalis | irx2 | CRISPR knockout of irx2 (iroquois homeobox 2). Custom mutant line generated for the Veenstra Lab. Ge... | NXR |
| Xla.cyp17a1emHorb | X. laevis | cyp17a1.L | CRISPR knockout of cyp17a1 (cytochrome P450 family 17 subfamily A member 1). Germline transmission n... | NXR |
| Xtr.arem1Horb | X. tropicalis | ar | CRISPR knockout in ar (androgen receptor). Germ line transmission confirmed. Animals carry a 2 base ... | NXR |
| Xtr.stmn2emHorb | X. tropicalis | stmn2 | CRISPR knockout of stmn2 (stathmin 2). Germline transmission not yet confirmed. Contact the NXR for ... | NXR |
| Xtr.esr1,esr2emHorb | X. tropicalis | esr1 esr2 | double CRISPR knockout of esr1 (estrogen receptor 1) and esr2 (estrogen receptor 2). Germline transm... | NXR |
| Xla.sox10em2Horb | X. laevis | sox10.L | CRISPR knockout of sox10 (SRY-box 10). Confirmed germ line transmission in sox10.L. Animals carry a ... | NXR |
| Xla.pkd2em2Horb | X. laevis | pkd2.L | CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Germ line tran... | NXR |
| Xla.pcntem2Horb | X. laevis | pcnt.L | CRISPR knockout of pcnt (pericentrin). Confirmed germline transmission. Animals carry a 2 base pair ... | |
| Xla.cyp19a1emHorb | X. laevis | cyp19a1.L | CRISPR knockout of cyp19a1.L (cytochrome P450 family 19 subfamily A member 1). Germline transmission... | NXR |
| Xtr.ptch1emHorb | X. tropicalis | ptch1 | CRISPR knockout of ptch1 (patched 1) enhancer region. Germline transmission not yet confirmed. Conta... | NXR |
| xtr.anks6emHorb | X. tropicalis | anks6 | CRISPR line targeting anks6 (ankyrin repeat and sterile alpha motif domain containing 6). Germline t... | NXR |
| Xtr.nphp1emHorb | X. tropicalis | nphp1 | CRISPR line targeting nphp1 (nephronophthisis 1 (juvenile)). Germline transmission not yet confirmed... | NXR |
| Xtr.twist1emHorb | X. tropicalis | twist1 | CRISPR knockout targeting twist1 (twist family bHLH transcription factor 1) enhancer region. Custom ... | NXR |
| Xtr.papss2emHorb | X. tropicalis | papss2 | CRISPR knockout of papss2 (3'-phosphoadenosine 5'-phosphosulfate synthase 2). Germline transmission ... | NXR |
| Xtr.esr2em2Horb | X. tropicalis | esr2 | CRISPR knockout in esr2 (estrogen receptor 2). Germline transmission confirmed. Custom mutant genera... | NXR |
| Xla.esr2emHorb | X. laevis | esr2.L | CRISPR knockout of esr2 (estrogen receptor 2). Germline transmission not yet confirmed. Contact the ... | NXR |
| Xla.tlr2emHorb | X. laevis | tlr2.L tlr2.S | CRISPR knockout of tlr2 (toll like receptor 2). Germline transmission not yet confirmed. Contact the... | NXR |
| Xla.il34emHorb | X. laevis | il34.L il34.S | CRISPR knockout of il34 (interleukin 34). Germline transmission not yet confirmed. Contact the NXR f... | NXR |
| Xla.emx2emHorb | X. laevis | emx2.L emx2.S | CRISPR knockout of emx2 (empty spiracles homeobox 2). Germline transmission not yet confirmed. Conta... | NXR |
| Xtr.plekhg3emHorb | X. tropicalis | plekhg3 | CRISPR knockout of plekhg3 (pleckstrin homology and RhoGEF domain containing G3). Germline transmiss... | NXR |
| Xtr.il34emHorb | X. tropicalis | il34 | CRISPR knockout of il34 (interleukin 34). Germline transmission not yet confirmed. Contact the NXR f... | NXR |
| Xtr.foxn1emHorb | X. tropicalis | foxn1 | CRISPR knockout of foxn1 (forkhead box N1). Germline transmission not yet confirmed. Contact the NXR... | NXR |
| Xtr.emx2emHorb | X. tropicalis | emx2 | CRISPR knockout of emx2 (empty spiracles homeobox 2). Germline transmission not yet confirmed. Conta... | NXR |
| Xtr.cd4emHorb | X. tropicalis | cd4 | CRISPR knockout od cd4 (cd4 receptor). Germline transmission not yet confirmed. Contact the NXR for ... | NXR |
| Xtr.bmpr1aemHorb | X. tropicalis | bmpr1a | CRISPR knockout targeting bmpr1a (bone morphogenetic protein receptor type 1A) enhancer region. Cust... | NXR |
| Xtr.Tg(hhex:trTA;TRE:ΔLL-Cdh1-GFP)Zorn | X. tropicalis | cdh1 | Custom inducible Tg/mutant line generated by the Zorn Lab. The bipartite transgene Tg(hhex:trTA;TRE:... | |
| Xtr.rspo2 em2NXR | X. tropicalis | rspo2 | CRISPR knockout of rspo2 (R-spondin 2). Germ line transmission confirmed. Animals carry a 10 base pa... | NXR |
| Xtr.fuz em2Horb | X. tropicalis | fuz | CRISPR knockout of fuz (fuzzy planar cell polarity protein). Germ line transmission confirmed. Anima... | NXR |
| Xla.trilem2NXR | X. laevis | tril.L tril.S | CRISPR knockout of tril (TLR4 interactor with leucine-rich repeats). Germline transmission not yet c... | NXR |
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