|
Xtr.zmym4emNXR
|
X. tropicalis |
zmym4
|
CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... |
NXR
|
|
Xtr.zeb2emNXR
|
X. tropicalis |
zeb2
|
CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... |
NXR
|
|
Xtr.zbtb21emHorb
|
X. tropicalis |
zbtb21
|
CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... |
NXR
|
|
Xtr.zbtb14emHorb
|
X. tropicalis |
zbtb14
|
CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... |
NXR
|
|
Xtr.ywhazemNXR
|
X. tropicalis |
ywhaz
|
CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). Ge... |
NXR
|
|
Xtr.xbp1emNXR
|
X. tropicalis |
xbp1
|
CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... |
NXR
|
|
Xtr.xbp1em2NXR
|
X. tropicalis |
xbp1
|
2nd X. tropicalis CRISPR line for xbp1 (X-box binding protein 1, a gene assocaited with Major Affec... |
NXR
|
|
Xtr.wwoxemHorb
|
X. tropicalis |
wwox
|
CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... |
NXR
|
|
Xtr.wt1emHorb
|
X. tropicalis |
wt1
|
CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... |
NXR
|
|
Xtr.wnt3em1NXR
|
X. tropicalis |
wnt3
|
CRISPR line targeting wnt3 (Wnt family member 3). Germ line transmission not yet confirmed, mutation... |
NXR
|
|
Xtr.wnt11bemNXR
|
X. tropicalis |
wnt11b
|
X. tropicalis CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), ... |
NXR
|
|
Xtr.wbp11emNXR
|
X. tropicalis |
wbp11
|
CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... |
NXR
|
|
Xtr.vwa2emNXR
|
X. tropicalis |
vwa2
|
CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... |
|
|
Xtr.vangl2emNXR
|
X. tropicalis |
vangl2
|
CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... |
NXR
|
|
Xtr.unc45bmZimml
|
X. tropicalis |
unc45b
|
Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. |
|
|
Xtr.tyremOchi
|
X. tropicalis |
tyr
|
An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... |
NBRP
|
|
Xtr.tyremNXR
|
X. tropicalis |
tyr
|
CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... |
|
|
Xtr.tyremKtsz
|
X. tropicalis |
tyr
|
An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... |
NBRP
|
|
Xtr.tupmZimml
|
X. tropicalis |
unknown
|
Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
|
|
Xtr.tspan8em3Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... |
NXR
|
|
Xtr.tspan8em2Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... |
NXR
|
|
Xtr.tspan8em1Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... |
NXR
|
|
Xtr.tp53em_del2/+_Vlemx
|
X. tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
|
|
Xtr.tp53em_del1/em_del2_Vlemx
|
X. tropicalis |
tp53
|
Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
|
|
Xtr.tp53em_del1/+_Vlemx
|
X. tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
|
|
Xtr.tlx3em2Horb
|
X. tropicalis |
tlx3
|
CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... |
|
|
Xtr.tlx3em1Horb
|
X. tropicalis |
tlx3
|
CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... |
|
|
Xtr.thratm,thrbtmShiyb
|
X. tropicalis |
thra
thrb
|
Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... |
|
|
Xtr.thratmShiyb
|
X. tropicalis |
thra
|
This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
|
|
Xtr.Tg(mlc2:dnfosl1-eGFP)Qi
|
X. tropicalis |
fosl1
|
Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... |
|
|
Xtr.tdrd1emNXR
|
X. tropicalis |
tdrd1
|
CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... |
NXR
|
|
Xtr.tbxtemJcsm
|
X. tropicalis |
tbxt
|
Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
|
|
Xtr.tbxt.2em2Jcsm
|
X. tropicalis |
tbxt.2
|
Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
|
|
Xtr.tbxt.2em1Jcsm
|
X. tropicalis |
tbxt.2
|
Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
|
|
Xtr.tbxt,tbxt.2emJcsm
|
X. tropicalis |
tbxt
|
Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
|
|
Xtr.tbx5emHorb
|
X. tropicalis |
tbx5
|
CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... |
|
|
Xtr.tbx2emHorb
|
X. tropicalis |
tbx2
|
CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. |
NXR
|
|
Xtr.syngap1 emNXR
|
X. tropicalis |
syngap1
|
CRISPR line targeting syngap1 (). Not screened for mutation or germ line transmission yet. Contact t... |
NXR
|
|
Xtr.supt5hmZimml
|
X. tropicalis |
supt5h
|
Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... |
|
|
Xtr.staremNXR
|
X. tropicalis |
star
|
CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... |
|
|
Xtr.srd5a3emNXR
|
X. tropicalis |
srd5a3
|
CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... |
|
|
Xtr.srd5a2emNXR
|
X. tropicalis |
srd5a2
|
CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... |
|
|
Xtr.sox3emHorb
|
X. tropicalis |
sox3
|
CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... |
NXR
|
|
Xtr.sox2emHorb
|
X. tropicalis |
sox2
|
CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... |
NXR
|
|
Xtr.sox2em2Horb
|
X. tropicalis |
|
CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... |
NXR
|
|
Xtr.sobp[em2NXR]
|
X. tropicalis |
sobp
|
2nd of 2 CRISPR knockout of sobp (sine oculis binding protein homolog ) X. tropicalis lines held by ... |
NXR
|
|
Xtr.snai2emNXR
|
X. tropicalis |
snai2
|
CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... |
NXR
|
|
Xtr.snai2em3NXR
|
X. tropicalis |
snai2
|
3rd CRISPR knockout line targeting snai2 (snail family zinc finger 2) in X. tropicalis. Germ line tr... |
NXR
|
|
Xtr.snai2 em2NXR
|
X. tropicalis |
snai2
|
CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... |
NXR
|
|
Xtr.snai1emNXR
|
X. tropicalis |
snai1
|
CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... |
NXR
|
