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Xtr.zmym4emNXR
|
X. tropicalis |
zmym4
|
CRISPR KO of zmym4 (zinc finger MYM-type containing 4) in X. tropicalis. Germline transmission confi... |
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Xtr.zeb2emNXR
|
X. tropicalis |
zeb2
|
CRISPR KO of zeb2 (zinc finger E-box binding homeobox 2), a gene associated with Mowat-Wilson syndro... |
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Xtr.zbtb21emHorb
|
X. tropicalis |
zbtb21
|
CRISPR knockout of zbtb21(zinc finger and BTB domain containing 21), Current mosaic founders, Not te... |
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Xtr.zbtb14emHorb
|
X. tropicalis |
zbtb14
|
CRISPR knockout of zbtb14 (zinc finger and BTB domain containing 14). Germ line transmission confirm... |
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Xtr.ywhazemNXR
|
X. tropicalis |
ywhaz
|
CRISPR KO of ywhaz (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). ge... |
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Xtr.xbp1emNXR
|
X. tropicalis |
xbp1
|
CRISPR KO of xbp1 ( X-box binding protein 1 ) a gene assocaited with Major Affected Disorder in huma... |
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Xtr.wwoxemHorb
|
X. tropicalis |
wwox
|
CRISPR knockout of wwox (WW domain containing oxidoreductase), a gene associated with esophageal can... |
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Xtr.wt1emHorb
|
X. tropicalis |
wt1
|
CRISPR knockout of wt1 (Wilms tumor 1). Germ line transmission confirmed. Animals carry a 5bp deleti... |
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Xtr.wnt11bemNXR
|
X. tropicalis |
wnt11b
|
CRISPR knockout of wnt11b (wingless-type MMTV integration site family, member 11B ), Germ line tran... |
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Xtr.wbp11emNXR
|
X. tropicalis |
wbp11
|
CRISPR knockout of wbp11 (WW domain binding protein 11). Germline transmission confirmed, F2s growin... |
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Xtr.vwa2emNXR
|
X. tropicalis |
vwa2
|
CRISPR knock out of vwa2 (von Willebrand factor A domain containing 2 ). Germ line transmission conf... |
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Xtr.vangl2emNXR
|
X. tropicalis |
vangl2
|
CRISPR knockout of vangl2 (VANGL planar cell polarity protein 2 ), a gene associated with neural tub... |
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Xtr.unc45bmZimml
|
X. tropicalis |
unc45b
|
Mutation affecting striated muscle identified in the Mill Hill screen for ENU-induced mutations. |
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Xtr.tyremOchi
|
X. tropicalis |
tyr
|
An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Ochi Lab. Th... |
NBRP
|
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Xtr.tyremNXR
|
X. tropicalis |
tyr
|
CRISPR knockout of tyr (tyrosinase), Confirmed germline transmission. Animal carry a 241bp insertion... |
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Xtr.tyremKtsz
|
X. tropicalis |
tyr
|
An albino line with CRISPR/Cas9-targeted mutation in tyrosinase (tyr) gene, made by the Suzuki Lab. ... |
NBRP
|
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Xtr.tupmZimml
|
X. tropicalis |
unknown
|
Mutation affecting axial development identified in the Mill Hill screen of ENU-induced mutations. |
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Xtr.tspan8em3Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 3rd of 3 tspan lines at... |
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Xtr.tspan8em2Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 2nd of 3 tspan lines at... |
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Xtr.tspan8em1Horb
|
X. tropicalis |
tspan8
|
CRISPR knockout of tspan8 (tetraspanin 8), Germ line transmission confirmed. 1of 3 tspan lines at th... |
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Xtr.tp53em_del2/+_Vlemx
|
X. tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated decay since due to the frame-shifting deletio... |
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Xtr.tp53em_del1/em_del2_Vlemx
|
X. tropicalis |
tp53
|
Two types of F1 tp53 heterozygotes, each with a distinct variant of a deletion (em_del1/+ and em_del... |
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Xtr.tp53em_del1/+_Vlemx
|
X. tropicalis |
tp53
|
Deletion is expected to give rise to nonsense-mediated
decay since due to the frame-shifting deleti... |
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Xtr.tlx3em2Horb
|
X. tropicalis |
tlx3
|
CRISPR mutant line targeting tlx3 (T cell leukemia homeobox 3). Germ lIne transmission was confirmed... |
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Xtr.tlx3em1Horb
|
X. tropicalis |
tlx3
|
CRISPR knockout of tlx3 (T cell leukemia homeobox 3). Confirmed germline transmission. Custom mutant... |
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Xtr.thratm,thrbtmShiyb
|
X. tropicalis |
thra
thrb
|
Double knockout oth thyroid receptor alpha nd thyroid receptor bets. Produced in the lab of Yun-Bo S... |
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Xtr.thratmShiyb
|
X. tropicalis |
thra
|
This line was created using TALENS targeting exon 4 (the third coding exon) of the X. tropicalis thr... |
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Xtr.Tg(mlc2:dnfosl1-eGFP)Qi
|
X. tropicalis |
fosl1
|
Fosl1 protein was mutated and truncated to generate 3 mutant polypeptides which then cloned into pc... |
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Xtr.tdrd1emNXR
|
X. tropicalis |
tdrd1
|
CRISPR knockout of tdrd1 (tudor domain containing 1). Germline transmission not yet confirmed. growi... |
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Xtr.tbxtemJcsm
|
X. tropicalis |
tbxt
|
Talen-induced 2bp deletion in exon 1 of tbxt (T-box transcription factor T) gene. Mutation destroys ... |
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Xtr.tbxt.2em2Jcsm
|
X. tropicalis |
tbxt.2
|
Talen-induced mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xtr.tbxt.2em1Jcsm
|
X. tropicalis |
tbxt.2
|
Talen-mediated mutant line. Talen-induced 7-bp deletion in third exon of T, brachyury homolog, gene ... |
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Xtr.tbxt,tbxt.2emJcsm
|
X. tropicalis |
tbxt
|
Double talen-induced mutant line. Talen induced 2-bp deletion in exon 1 of tbxt and 7 bp deletion in... |
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Xtr.tbx5emHorb
|
X. tropicalis |
tbx5
|
CRISPR knockout of tbx5 (T-box 5 ), Confirmed germline transmission. Custom mutant generated by Horb... |
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Xtr.tbx2emHorb
|
X. tropicalis |
tbx2
|
CRISPR knockout of tbx2 (T-box 2), Current mosaic founders, Not tested for germline transmission. |
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Xtr.supt5hmZimml
|
X. tropicalis |
supt5h
|
Mutation affecting eye development and melanophore migration identified in the Mill Hill screen for ... |
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Xtr.staremNXR
|
X. tropicalis |
star
|
CRISPR knockout of STAR (steroidogenic acute regulatory protein). Germ line transmission not yet con... |
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Xtr.srd5a3emNXR
|
X. tropicalis |
srd5a3
|
CRISPR knockout of srd5a3 (steroid 5 alpha-reductase 3), Germ line transmission confirmed. F1 growin... |
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Xtr.srd5a2emNXR
|
X. tropicalis |
srd5a2
|
CRISPR knockout of srd5a2 (steroid 5 alpha-reductase 2), Confirmed germ line transmission. animals c... |
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Xtr.sox3emHorb
|
X. tropicalis |
sox3
|
CRISPR knockout of sox3 (SRY-box 3), Current mosaic founders, Not tested for germline transmission. ... |
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Xtr.sox2emHorb
|
X. tropicalis |
sox2
|
CRISPR knockout of sox2 (SRY-box 2). Custom mutant line. Germ line transmission confirmed. Animals c... |
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Xtr.snai2emNXR
|
X. tropicalis |
snai2
|
CRISPR knockout of snai2 (snail family zinc finger 2) in X. tropicalis. Germ line transmission confi... |
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Xtr.snai1emNXR
|
X. tropicalis |
snai1
|
CRISPR knockout of snai1 (snail family zinc finger 1) in X. tropicalis. germline transmission confir... |
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Xtr.smad4mZimml
|
X. tropicalis |
smad4
|
Mutation affecting haematopoiesis identified in a screen for ENU-induced mutations at Mill Hill. Pos... |
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Xtr.slc2a7.tyr.hps6tmHUARC
|
X. tropicalis |
hps6
slc2a7
tyr
|
triple knock out (3KO) line generated by crossing mutant lines with KO of tyr, hps6, and slc2a7 |
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Xtr.six1em2NXR
|
X. tropicalis |
six1
|
CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
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Xtr.six1em1NXR
|
X. tropicalis |
six1
|
CRISPR knockout of six1 (SIX homeobox 1), a gene associated with branchiootorenal syndrome and branc... |
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Xtr.shroom3emHorb
|
X. tropicalis |
shroom3
|
CRISPR knockout of shroom3 (shroom family member 3), Current mosaic founders, Germ line transmissio... |
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Xtr.sf3b4emNXR
|
X. tropicalis |
sf3b4
|
CRISPR knockout of sf3b4 (splicing factor 3b subunit 4) in X tropicalis. sf3b4 is a gene associated ... |
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Xtr.rxrgemHorb
|
X. tropicalis |
rxrg
|
Description: CRISPR knockout of rxrg (retinoid X receptor gamma). Confirmed germline transmission. C... |
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