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XB-LINE-1381
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Line Name: Xla.hmgcremHorb
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| Summary | |
|---|---|
| Synonym: | hmg-coa, Xla.hmgcrtmHorb |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | Xla.J-strainNXR |
| Maternal Line: | Xla.J-strainNXR |
| Description: | CRISPR knockout of hmgcr (3-hydroxy-3-methylglutaryl-CoA reductase). Germline transmission confirmed. gRNA KOs both Xla.hmgcr.L and Xla.hmgcr.S. Animals carry a 31 base pair deletion on the L allele and a 16 base pair deletion on the S allele. Contact the NXR for more details. |
| Phenotype Description: | -31 base pair mutation sequence on the L allele TGAAGTCCGAGAC-------------------------------CTACCTTTACCC and -16 base pair mutation sequence on the S allele AAAGGTAGG----------------CCACGGGCAATAT. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | Horb Lab |
| Line Type: | Mutant |
| Mutated Gene(s): | hmgcr.L hmgcr.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2021 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2021 | F2 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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