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XB-LINE-1260
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Line Name: Xla.pkd2emHorb
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| Summary | |
|---|---|
| Synonym: | Xla.pkd2tmHorb |
| Species: | Xenopus laevis |
| Background Strain: | Xla.Outbred |
| Paternal Line: | Xla.J-strainNXR |
| Maternal Line: | Xla.J-strainNXR |
| Description: | CRISPR knockout of pkd2 (polycystin 2, transient receptor potential cation channel ). Germ line transmission confirmed. Animals carry a 16 base pair deletion or a 20 base pair deletion in pkd2.L. |
| Phenotype Description: | -16 base pair mutation sequence GCGTGGGAGC----------------CACACGGAAC and -20 base pair mutation sequence GTCTGTACTG--------------------GGACAATGGC. Associated with human autosomal dominant polycystic kidney disease. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | Horb Lab |
| Line Type: | Mutant |
| Mutated Gene(s): | pkd2.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2010 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2010 | F2+ | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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