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XB-LINE-1270
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Line Name: Xla.slc16a2emHorb
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| Summary | |
|---|---|
| Synonym: | Xla.slc16a2tmHorb |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | Xla.J-strainNXR |
| Maternal Line: | Xla.J-strainNXR |
| Description: | Double CRISPR knockout of slc16a2 (solute carrier family 16, member 2 (thyroid hormone transporter). Germ line transmission confirmed. Animals carry a 29 base pair deletion in slc16a2.L and a 20 base pair deletion in slc16a2.S. Custom mutant generated by the Horb Lab for Dan Buchholz. Contact the NXR for more details. |
| Phenotype Description: | -29 base pair mutation sequence in L allele TCAGGGGTCG-----------------------------TAGTGCTGGC and -20 base pair mutation sequence in S allele GAGGGGTCGG--------------------CTGGGTCGTAG. Associated with human Allan-Herndon-Dudley syndrome. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | Horb Lab |
| Line Type: | Mutant |
| Mutated Gene(s): | slc16a2.L slc16a2.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2001 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2001 | F2 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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