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XB-LINE-1275
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Line Name: Xla.wdpcpemHorb
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| Summary | |
|---|---|
| Synonym: | Xla.wdpcptmHorb |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of wdpcp (WD repeat containing planar cell polarity effector). Germ line transmission confirmed. Animals carry a 20 base pair deletion in wdpcp.L. Mutant line generated by Horb Lab. Contact the NXR for more details. |
| Phenotype Description: | -20 base pair mutation sequence TAGCATGCAAGACCT--------------------TGCCAGTCGAT. Associated with human congenital heart defects, hamartomas of tongue, and polysyndactyly. |
| Color Morph: | pigmented |
| Breeding Type: | UNKNOWN |
| Lab of Origin: | Horb Lab |
| Line Type: | Mutant |
| Mutated Gene(s): | wdpcp.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2017 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2017 | F2+ | Order | F3 adults available | |
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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