Summary Attributions

Line Name: Xtr.ap3d1mZimml

Line Images [+] show captions [-] hide captions Xtr.ap3d1 mutant embryos (phenotype called seasick /ssk) display fused otoconia and balance defects, with punctate pigmentation and a reduced number of iridophores.

Summary
Synonym:	Seasick, sskmh6
Species:	Xenopus tropicalis
Background Strain:	Xtr.Nigerian1EXRC
Paternal Line:
Maternal Line:
Description:	Mutation affecting inner ear otoconia identified in the Mill Hill screen for ENU-induced mutations. Segregated from same founder female as muzak. Nonsense mutation in the vesicle transport adaptor protein ap3d1. Reference: Ironfield, H.V.; (2011) Genetic studies of inner ear development in Xenopus tropicalis. Doctoral thesis. http://discovery.ucl.ac.uk/1324536/
Phenotype Description:	Homozygous tadpoles show enlarged inner ear otoconia and vestibular defects and punctate melanocytes.
Color Morph:	pigmented
Breeding Type:	OUTBRED
Lab of Origin:	Zimmerman Lab
Line Type:	Mutant
Mutated Gene(s):	ap3d1
MTA Required:	Yes
Public:	Yes
Catalogue Number:

Stock Center	RRID	Generation	Availability	Mutant Details	Information
NXR (US)
EXRC (Europe)	EXRC_6007
NBRP (Japan)
XLRRI (US)

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