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XB-LINE-2341
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Line Name: Xtr.lmnaem2Horb
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus tropicalis |
| Background Strain: | Xtr.Nigerian1NXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of lmna (lamin A/C). Confirmed germline transmission. Mutants carry an 11 base pair deletion. Custom mutant generated by Horb Lab. Contact the NXR for more details. |
| Phenotype Description: | -11 base pair mutation sequence GGAAGAGGTGGAT-----------ATACGTGCGGCT. Associated with human autosomal dominant Emery-Dreifuss muscular dystrophy 2. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | lmna |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_3193 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_3193 | F1 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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