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XB-LINE-2365
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Line Name: Xla.tracem2Horb
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | Xla.tracemHorb |
| Maternal Line: | Xla.tracemHorb |
| Description: | CRISPR knockout of trac (T cell receptor alpha constant). Guide targeting S alloallele was injected into Xla.trac{emHorb} to generate a double knockout. Germline transmission not yet confirmed. Contact the NXR for more details. |
| Phenotype Description: | trac.S sgRNA injected into a -14 base pair heterozygous trac.L intercross. -14 base pair mutation sequence GGGAC - - - - - - - - - - - - - - CTCAGGTWGCTT. S mutation sequence to follow. Associated with immunodeficiency 7 in humans. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | trac.L trac.S |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2202 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2202 | F0 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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