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XB-LINE-2024
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Line Name: Xla.rag2emNXR
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.wildtype1NXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of rag2 (recombination activating 2). Germ line transmission confirmed. Animals carry a 5 base pair deletion. Contact NXR for more details. |
| Phenotype Description: | -5 base pair mutation sequence GACCCCAGAC-----CGGGGAAATT. Associated with human combined cellular and humoral immune defects with granulomas. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | rag2.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2166 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2166 | F2 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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