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XB-LINE-2030
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Line Name: Xla.il2rgem2NXR
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| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of il2rg (interleukin 2 receptor subunit gamma). Germ line transmission confirmed. Animals carry a 13 base pair deletion. Contact NXR for more details and updates. |
| Phenotype Description: | -13 base pair mutation sequence AAACATGACAAT-------------CTGATCTTCATCACCC. Associated with combined T cell and B cell immunodeficiency in humans. |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | il2rg.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2185 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2185 | F1 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
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