|
XB-LINE-2389
|
Line Name: Xla.sox10em2Horb
|
|
| Summary | |
|---|---|
| Synonym: | |
| Species: | Xenopus laevis |
| Background Strain: | Xla.J-strainNXR |
| Paternal Line: | |
| Maternal Line: | |
| Description: | CRISPR knockout of sox10 (SRY-box 10). Confirmed germ line transmission in sox10.L. Animals carry a 13 base pair deletion. Mutant line generated by Horb Lab. Contact the NXR for more details. |
| Phenotype Description: | -13 base pair mutation sequence AGACC-------------TGCTCACTCCAGTCCAGA. Associated with peripheral demyelinating neuropathy, central dysmyelination, Waardenburg syndrome, and Hirschsprung disease (PCWH). |
| Color Morph: | pigmented |
| Breeding Type: | OUTBRED |
| Lab of Origin: | NXR |
| Line Type: | Mutant |
| Mutated Gene(s): | sox10.L |
| MTA Required: | No |
| Public: | Yes |
| Catalogue Number: | NXR_2015 |
| Stock Center | RRID | Generation | Availability | Mutant Details | |
|---|---|---|---|---|---|
| NXR (US) | NXR_2015 | F1 | Order | ||
| EXRC (Europe) | |||||
| NBRP (Japan) | |||||
| XLRRI (US) | |||||
Back to Search Lines