Xenbase Image ID: 134847

Fig. 3. The effect of Xdsh mRNA depends on the site of injection. A single prospective dorsal (A) or ventral (B,D) vegetal blastomere of cleavage-stage embryos (8-16 cells) was injected with 0.4 ng of Xdsh mRNA. Phenotypes of the injected neurulae (A,B) and of tadpoles at stages 40-42 (C,D) are presented. Axis duplications are clearly visible in embryos injected with Xdsh RNA in a ventral blastomere (B,D). Embryos, injected ventrally with 0.4 ng of a control ÆXdsh mRNA (C), are indistinguishable from normal tadpoles or from the tadpoles, injected dorsally with Xdsh mRNA (as in A). Note that three embryos in D have completely duplicated body axes including most anterior and posterior structures, whereas in one embryo both dorsal axes oppose each other and posterior development is inhibited. Image published in: Sokol SY et al. (1995) Copyright © 1995. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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