Xenbase Image ID: 138215

Figure 1. Induction of postural asymmetry and skeletal distortion by UL. A,B, Removal of all labyrinthine end organs (A1,A3) from the otic capsule on the left side in a stage 55 tadpole (A2,A4) causes a persistent leftward bending of the body/tail, during the premetamorphic larval period (B), mainly along the first 10 myotomes (m); A4 is a close-up of the boxed area in A2, and A3 was obtained from a control animal other than that shown in A1. C, Top (C1) and frontal (C2) view of a postmetamorphic young adult frog (stage 66) subjected to a UL at larval stage 55, illustrating the typical twisted body shape and asymmetric limb positions. D, Microphotograph of a 3D reconstructed μ-CT scan of the distorted skeleton of a stage 66 adult Xenopus subjected to a UL at larval stage 55. Red asterisks in A–D indicate the side of the lesion; ac, pc, hc, anterior, posterior vertical, horizontal semicircular canals; oc, otic capsule; sa, saccule; ut, utricle. Image published in: Lambert FM et al. (2013) Copyright © 2013. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Larger Image Printer Friendly View

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