Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Xenbase Image ID: 150818

Fig. 4. Gene Set Enrichment Analysis (GSEA) of dorsal and ventral gene signatures. (A–B) The dorsal gene signature (comprised of 107 genes) positively correlated with Chordin (P<0.001), a Spemann organizer marker, and negatively correlated (or anti-correlated) with BAMBI (P<0.001), a marker of ventral tissues. (C–D) The ventral signature (which contains 70 genes) positively correlated with BAMBI (P<0.001), while it negatively correlated with Chordin (P<0.001). (E) SMC1A, used here as a negative control, did not correlate with the dorsal (P=0.355) nor the ventral (not shown) signature. (F) Pkdcc, a novel dorsal gene described here, significantly correlated with the dorsal gene signature (P<0.001).

Image published in: Ding Y et al. (2017)

Copyright © 2017. Image reproduced on Xenbase with permission of the Publisher, Elsevier B. V.

Larger Image
Printer Friendly View

Return to previous page
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.10.0

Major funding for Xenbase is provided by grant P41 HD064556