Click here to close Hello! We notice that you are using Internet Explorer, which is not supported by Xenbase and may cause the site to display incorrectly. We suggest using a current version of Chrome, FireFox, or Safari.

Xenbase Image ID: 158283

Fig 2. Test crosses between animals carrying tyr-mutated leapfrog transplants and albinos demonstrate germline transmission of mutant alleles. (A) Leapfrog transplant-bearing male (pigmented) is shown amplexed with an albino tyr−/− female. (B) Leapfrog transplant-bearing female (pigmented) is shown amplexed with an albino tyr−/− male. (C) Examples of F1 progeny from the cross in A grown to tadpole stage. These tadpoles are albino because they inherited tyr mutant alleles from both F0 parents. Therefore the leapfrog-generated frog carries gametes derived from CRISPR-mutated PGCs. The inset in C shows an unrelated pigmented tadpole at roughly the same stage for comparison.

Image published in: Blitz IL et al. (2016)

Copyright © 2016. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.

Larger Image
Printer Friendly View

Return to previous page
Xenbase: The Xenopus laevis and X. tropicalis resource.
Version: 4.12.3

Major funding for Xenbase is provided by grant P41 HD064556