XB-IMG-171227
Xenbase Image ID: 171227
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Figure S3. Related to Fig. 2; Expression of gastrulation genes in rapgef5
morphants. (A) At stage 10, expression of numerous gastrulation markers (gsc,
chordin, fgf8, otx2, vent, t, not and noggin) are less affected by depletion of Rapgef5
compared to foxj1 or xnr3 (See Fig. 2A). Vegetal views with dorsal to the top. (B)
Injection of a control MO or a control CRISPR (targeting tyrosinase) does not affect
foxj1 expression (C) Co-injection of human RAPGEF5 mRNA can rescue the loss of
foxj1 expression in Rapgef5 morphants, demonstrating the specificity of the MO. Triple
asterisks indicate P<0.005. Image published in: Griffin JN et al. (2018) Copyright © 2018. Image reproduced with permission of the Publisher, Elsevier B. V.
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