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Fig. 1. Geminin regulates epidermal, mesodermal and endodermal gene expression. Geminin RNA or morpholino/MO-injected regions are oriented rightwards, indicated by yellow arrowheads, and lineage is labeled by β-galactosidase RNA co-injection and Red-gal (Mix.2, Brachyury/Xbra, and Sox17 at stage 11) or X-gal staining. Embryos are stage 10.5-11, except for Epidermal keratin/Epiker and Sox17 (right), which are stage 12-13. Views are indicated: (veg, vegetal; post, posterior).
Image published in: Lim JW et al. (2011)
Copyright © 2011. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
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| krt12.4.L | epidermal keratin, epi-keratin, epiker, cytokeratin, Epidermis-specific keratin, xK81, EpK, cytok, E-keratin, ck81, K81, EpiK, xk81a1, xk81a | X.laevis | Throughout NF stage 12 to NF stage 13 | animal cap
ectoderm
| | a2m.S | endodermin, Alpha2-macroglobulin, endod, Edd, edd | X.laevis | Throughout NF stage 10.5 to NF stage 11 | blastopore lip
| | mix1.S | mix.1, mix.2, mix2, tMix | X.laevis | Throughout NF stage 10.5 to NF stage 11 | dorso-lateral marginal zone
dorsal marginal zone
| | sox17a.L | xSox17alpha1, xSox17alpha2, tSox17alpha, Xsox17-alpha, Sox17alpha, sox17-alpha, xsox17a, xsox17, Xsox17alpha, sox17 alpha | X.laevis | Throughout NF stage 12 to NF stage 13 | endoderm
| | tbxt.S | Xbra, X-bra, bra, Xbrachyury, brachyury, ntl, t-a, t-b, t | X.laevis | Throughout NF stage 10.5 to NF stage 11 | mesoderm
| | hhex.L | XHex, tHex, hex | X.laevis | Throughout NF stage 10.5 to NF stage 11 | endomesoderm
| | post.L | Xpo, loc108704914 | X.laevis | Throughout NF stage 12 to NF stage 13 | blastopore
ventral marginal zone
ventro-lateral marginal zone
dorso-lateral marginal zone
dorsal marginal zone
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