Fig. 6. In vivo b2m silencing results in delayed MHC disparate skin graft rejection.(A) Adult anti-b2m shRNA transgenic LG-6 clones (LG-6 Tg) and control naïve LG-6 animals (LG-6 C) grafted with a MHC disparate J skin. Skin graft rejection was monitored daily at 21°C until complete rejection. (B) Adult outbred frogs carrying either anti-b2m shRNA (OB β2-m shRNA) or scram shRNA (OB scram shRNA) transgenes were grafted with a MHC disparate J skin. Skin graft rejection was monitored at 21°C until complete rejection. Each group consisted of 3 animals and the graphs show the average skin graft rejection of the group. P values were determined using the Student's t-test.
Image published in: Nedelkovska H et al. (2013)
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