Fig. 6. BMP4 can relieve geminin’s suppression of epidermal development. (A-F) Double in situ hybridizations with epidermal keratin (aqua) and geminin (pink) probes at stages 10- (A), 10+ (B, C), 12.5 (D) or 12 (E, F). A and C are dorsal views (arrowheads mark the dorsal lip); B, E and F are animal hemisphere views. (E) Coinjection of BMP4 and geminin; dark-purple tissue expresses both epidermal keratin and injected geminin. (F) Coinjection of geminin and GFP. Epidermal keratin expression is suppressed in regions expressing injected geminin.
Image published in: Kroll KL et al. (1998)
Copyright © 1998. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
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