Figure 2. Photomicrographs of sagittal (A,E,G) and transverse (B–D,F) sections through the mammillary and tuberal hypothalamus of Xenopus, showing the expressions of xShh (A), Nkx2.1 (B), and Isl1 (C) and the combined expressions of Isl1 and Nkx2.1 (D,E), Isl1 and Otp (F), Nkx2.1 and Nkx2.2 (G), and Pax7 and Nkx2.1 (H). Developmental stages are indicated in each photograph. The schematic representation at the bottom summarizes the boundaries between the different basal hypothalamic subdivisions and the combinatorial code of markers of each region. The yellow lines indicate the limit between two adjacent regions revealed by the different markers. A magenta-green version of this figure is provided as Supporting Information Fig. 1. Scales bars = 100 μm in A,F–H, B (valid for C,D); 50 μm in E.
Image published in: Domínguez L et al. (2014)
Copyright © 2014. Image reproduced with permission of the Publisher, John Wiley & Sons.
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