Fig. 9. DN-Rarγ2 mRNA rescues posterior Hox expression in Rarγ2 MO embryos. (A-D) Embryos injected unilaterally at 2- or 4-cell stage. Injected side is indicated by magenta β-gal lineage tracer. (A) 2.5 ng Rarγ2.1 MO+2.5 ng Rarγ2.2 MO or (B) 5 ng Rarγ2.1 MO+5 ng Rarγ2.2 MO diminishes Hoxc10 expression and curves the embryo axis. (C,D) 2 ng DN-Rarγ2 mRNA partially rescues this effect and expands neural expression of Hoxc10. Tailbud embryos shown in dorsal view with anterior to left. (E) Detailed scoring of the rescue experiment.
Image published in: Janesick A et al. (2014)
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