Fig. 4. (a) Steady state solutions to (7) plotted against λAM,B for A=5. Thick solid lines represent the mesoderm steady state, thin solid lines represent the anterior mesendoderm steady state and dashed lines represent the unstable steady state. Fold bifurcations mark the appearance and the disappearance of the steady states. (b) Solution structure in terms of the bifurcation parameters λAM,B and λA,M, these representing the folds that determine the maximum rates of production of Brachyury and Mix in response to activation by Activin. (c) Solution structure in terms of the bifurcation parameters λAM,B and λM,G, these representing the folds that determine the maximum rates of production of Brachyury in response to activation by Activin and Goosecoid in response to Mix. Unless otherwise stated, parameters were chosen as in Table 2.
Image published in: Brown LE et al. (2014)
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