Larger Image S7 Overexpression of β-catenin mRNA(β-cat. RNA; Fig. S7) did not consistently lead to increased numbers of MCCs or SSCs in the epidermis at stage 32 (Fig. S 7 C and D), although it is note worthy that in two out of twelve specimens a massive increase in MCCs occurred, indicating a potentially more complex relationship between canonical Wnt signaling and MCC specification. In summary, our data revealed a developmental requirement for ATP4a-dependent Wnt/β-catenin signaling during Foxj1- mediated motile ciliogenesis and Foxa1-mediated specification of SSCs in the mucociliary epidermis of Xenopus embryos. Image published in: Walentek P et al. (2015) Copyright © 2015. Image reproduced with permission of the Publisher, Elsevier B. V.
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