FIG. Is Exposure of Xenopus gastrulae to hthium or ectoplc Xwnt-8 results in the loss of anterior structures. Embryos were treated with lithium at gastrula stages 12 (B), 11 (C), 10 (D), and 9 (E) or injected with pCSKA-Xwnt-8 m the dorsal marginal zone at the 4-ceU stage (F) and allowed to grow to the tailbud stage (stage 30). Control embryos (A) possess eyes (arrow) and cement gland (arrowhead) while these structures are reduced or absent in the lithium-treated and Xwnt-8-misexpressing embryos. The scale of the extent of posteriorization (P1-P4) corresponds to that described in Yamaguchl and Shinagawa (1989).
Image published in: Fredieu JR et al. (1997)
Copyright © 1997. Image reproduced with permission of the Publisher, Elsevier B. V.
| Experiment + Assay | Source | Phenotypes and Disease | ||
|---|---|---|---|---|
| Xla Wt + LiCl + NF29/30 (whole-mount microscopy) | Fig.1.b |
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| Xla Wt + LiCl + NF29/30 (whole-mount microscopy) | Fig.1.c |
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| Xla Wt + LiCl + NF29/30 (whole-mount microscopy) | Fig.1.d |
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| Xla Wt + LiCl + NF29/30 (whole-mount microscopy) | Fig.1.e |
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| Xla Wt + wnt8b + NF29/30 (whole-mount microscopy) | Fig.1.e |
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