Supp. Fig 3. Pharmacological inhibition of FGF signaling at mid-neurulation does not affect pax7 patterning. Control embryos were grown in DMSO (carrier) from stage 12 to stages 18–22, they exhibit normal sox2, hoxb9 and pax7 expression (100% of the embryos). In contrast, sibling embryos grown in SU5402 between stages 12 and 18–22 have severe defects in neural patterning (hoxb9) while sox2 is normal. In this condition, pax7 expression remains largely comparable to controls (60% of the embryos).
Image published in: Maczkowiak F et al. (2010)
Copyright © 2010. Image reproduced with permission of the Publisher, Elsevier B. V.
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