Fig. S11. Prdm12 knockdown and overexpression affects swimming movements. (A) Quantification of the embryos with normal, impaired and paralyzed swimming movements. Number in parentheses indicates the number of embryos analyzed. (8) In situ hybridization analysis of En1 expression in uninjected controls, mouse Prdm12 mRNA (200 pg/blastomere) or Prdm12 MO injected stage 28 embryos. Transverse sections at the level of the posterior hindbrain are shown. Note the strongly increased expression of En1 in the Prdm12-injected embryos and the absence of En1 expression in the Prdm12 MO injected embryos. UI : uninjected.
Image published in: Thélie A et al. (2015)
Copyright © 2015. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| en1.L | en-1, en1-a, en1-b, eng1, engrailed 1, engrailed-1, xen1 | X. laevis | Throughout NF stage 28 | hindbrain |
Image source: Published
| Experiment + Assay | Source | Phenotypes and Disease | ||
|---|---|---|---|---|
| Xla Wt + Flag-Mmu.prdm12 + NF28 (in situ hybridization) | Fig.S11.a |
| ||
| Xla Wt + prdm12 MO + NF28 (in situ hybridization) | Fig.S11.a |
|
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