Larger Image Fig. 7. Xseb4R is regulated by proneural and neurogenic genes. (A,C,E) Dorsal views of embryos after injection of the indicated genes and stained for Xseb4R expression (dark blue). β-galactosidase activity is shown in light blue. (B,D,F) One representative embryo for each injection series is shown at high magnification. (A,B) XNgnr1 strongly activates Xseb4R transcription in neural and non-neural ectoderm. (C,D) XNeuroD equally induces ectopic Xseb4R expression. (E,F) Activation of Notch signalling by injection of ICD-Notch reduces the expression of Xseb4R. Image published in: Boy S et al. (2004) Copyright © 2004. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License. Gene Synonyms Species Stage(s) Tissue rbm38.L rnpc1, XSeb4R X. laevis Sometime during NF stage 17 to NF stage 20 spinal cord nervous system eye eye primordium neural plate Image source: Published Experiment + Assay Source Phenotypes and Disease Xla Wt + neurog2 + NF15 (in situ hybridization) fig.7.a, b Expression Phenotype increased amount rbm24.L expression in neuroectoderm increased amount rbm24.L expression in non-neural ectoderm Xla Wt + neurod1 + NF15 (in situ hybridization) fig.7.c, d Expression Phenotype increased amount rbm24.L expression in neuroectoderm increased amount rbm24.L expression in non-neural ectoderm Xla Wt + canotch1 + NF15 (in situ hybridization) fig.7.e, f Expression Phenotype decreased amount rbm24.L expression in neural plate decreased amount rbm24.L expression in neuroectoderm Permanent Image Page Printer Friendly View XB-IMG-152331