Fig. 4. Tissue-specific developmental regulation of Sox3 in the intestine during Xenopus laevis metamorphosis. (A) Sox3 is highly expressed only during metamorphosis. Total intestinal RNA at different stages was analyzed by qRT-PCR. Note that little Sox3 expression was found either before (stage 54-56) or at the end of metamorphosis (stage 66). (B) Sox3 is expressed only in the intestinal epithelium. Total RNA was isolated from intestinal epithelium (Ep) and the rest of the intestine (non-Ep) at different stages of development, 56 (premetamorphosis), 61 (climax), and 66 (end of metamorphosis), and analyzed by qRT-PCR. Note that Sox3 was highly expressed only in the Ep at the climax of metamorphosis when stem cells were forming or proliferating. See [105] for details.
Image published in: Fu L and Shi YB (2017)
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