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Fig. 6 – Comparative analysis of the region in the Xenopus and human APP cDNAs responsible for the aberrant promoter activity. Identical nucleotides are white on a black background. The transcription start site inXenopus APP cDNA is indicated by an asterisk and the direction of transcription by an arrow. The codon representing the start methionine is underlined. The N-terminal region of the aberrant APP-GFP protein fragment is presented below the alignment. The positions of exons 16, 17 and 18 of the APP gene are indicated by vertical lines.

Image published in: Collin RW and Martens GJ (2006)

Copyright © 2006. Image reproduced with permission of the Publisher, Elsevier B. V.

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