Fig. 4. Wdpcp maintains membrane stability via Rho Kinase and Myosin activity. (A) Epidermal tissue injected with Wdpcp-MO displaying severe membrane blebbing. (B) Y27632, a Rho kinase inhibitor, blocked the blebbing phenotype in Wdpcp morphants. (C) The same epidermis shown in B started blebbing again after 1 hour washout of Y27632. (D) Quantification of blebbing index; Wdpcp-MO n = 24; Y27632 n = 44; Wash n = 23; Blebbistatin n = 83. The scale bars are 10 lm.
Image published in: Park TJ et al. (2015)
Copyright © 2015. This image is reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
Permanent Image Page
Printer Friendly View
XB-IMG-153903