Fig. 6. Tbx2 inhibition of FGF signaling is critical for formation of head structures. (A-G) Four-cell stage embryos were injected in the animal region as indicated with Tbx2 MO (40 ng), CO MO (60 ng) and Flrt3 MO (60 ng) and cultured to tadpole stages with or without chemical treatment. SU5402 (20 μM) or DMSO was treated to the injected embryos from stage 15–20. Control, an uninjected embryo. Lateral views with anterior to the left. (H) Quantification of the phenotypes shown in (A-G) in terms of eye formation. n, the total number of embryos analyzed. + eye, embryo with eyes; - eye, embryo with no eyes.
Image published in: Cho GS et al. (2017)
Copyright © 2017. Image reproduced with permission of the Publisher, Elsevier B. V.
Permanent Image Page
Printer Friendly View