Figure 5. Inhibition of Notch signaling by dibenzazepine (DBZ) blocks the regulation of gene expression by T3. Total RNA was extracted from the intestine of tadpoles treated with T3 for 3 or 5 days in the presence of DMSO or DBZ as shown in Fig. 4A. quantitative real-time RT-PCR was carried out for Hairy1 (A), Hairy2b (B), LGR5 (C), and IFABP (D). Error bars represent the SEM (n = 3). The results were analyzed by Student's t-test (*, p < .05; **, p < .01). Abbreviation: DBZ, dibenzazepine.
Image published in: Hasebe T et al. (2017)
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