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Figure 3. Expression of Pax3 and Zic1 at the NPB. (A) Developmental expression of Pax3 and Zic1 at the NPB in stage-matched embryos (the stages are indicated in the top right corner). Dorsal views, anterior to top. (B) Transverse section through neurula stage embryos illustrating the relative position of Pax3 and Zic1 in the deeper layer of the ectoderm (arrowheads). Pax3 is also detected in the superficial layer of the ectoderm (arrows), and Zic1 expression domain expands more laterally (bracket) than Pax3. (C) Schematic representation of cross-sections through neurula stage embryo showing the domain of expression of the Pax3 and Zic1 (purple). (D) Xhe and Pax3 are coexpressed in the HG at the tailbud stage. Frontal views.

Image published in: Hong CS and Saint-Jeannet JP (2007)

Copyright © 2007. Image reproduced with permission of the Publisher, American Society for Cell Biology (ASCB). This is an Open Access article.

GeneSynonymsSpeciesStage(s)Tissue
zic1.Lodd-paired-like, opl, Zic-r1, Zic-related-1X. laevisSometime during NF stage 18 to NF stage 19neural crest
neural plate border
ectoderm
sensorial layer of neurectoderm
pax3.Lcdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisSometime during NF stage 18 to NF stage 19neural crest
neural plate
neuroectoderm outer layer
pax3.Lcdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisThroughout NF stage 28hatching gland
astl3a.1.LLOC100491875, uvs.2-like, xheX. laevisThroughout NF stage 28hatching gland
zic1.Lodd-paired-like, opl, Zic-r1, Zic-related-1X. laevisThroughout NF stage 11.5 
zic1.Lodd-paired-like, opl, Zic-r1, Zic-related-1X. laevisSometime during NF stage 12 to NF stage 13 
zic1.Lodd-paired-like, opl, Zic-r1, Zic-related-1X. laevisThroughout NF stage 16 
pax3.Lcdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisThroughout NF stage 11.5 
pax3.Lcdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisSometime during NF stage 12 to NF stage 13 
pax3.Lcdhs, hup2, pax-3, pax3-a, pax3-b, Waardenburg syndrome 1, ws1, xpax3X. laevisThroughout NF stage 16 

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