Figure 6. A Long Temperature Gradient Induces a Mesodermal Induction Defect and Reveals a Resynchronizing Mechanism (A) Xbra expression after MBT. Time course of Xbra expression in gradient embryos treated in the side to side and top to bottom directions. Unstained and mock-treated control embryos are shown for comparison. (B and C) Phenotype and survival of embryos two weeks after treatment with a side-to-side (B) or top-to-bottom (C) gradient. “Alive” includes embryos that survived with a generally normal phenotype, and “abnormal” includes embryos that did not survive and embryos that experienced clear developmental defects, such as dorsalization, ventralization, and bent body axes.
Image published in: Anderson GA et al. (2017)
Copyright © 2017. Image reproduced with permission of the publisher and the copyright holder. This is an Open Access article distributed under the terms of the Creative Commons Attribution License.
| Gene | Synonyms | Species | Stage(s) | Tissue |
|---|---|---|---|---|
| tbxt.L | bra, brachyury, ntl, t, t-a, t-b, X-bra, Xbra, Xbrachyury | X. laevis | Sometime during NF stage 10 to NF stage 11.5 | mesoderm marginal zone blastopore lip |
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